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Peptide record

TPDB19636

Antibacterial Toxicity modified_plain modified
14 amino acids
Basic Information
3D PDB MODEL
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TPDB19636
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 14-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
FXXKXXFXXKKKKK
Physicochemical Analysis
C54H92N14O9
ARNDCEQGHILMPSTWYV
K
1081.41
11.21
6
0
2
+6
3.68
-1.271
0.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
6
K
0
M
2
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 6 M: 0 F: 2 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
14
C54H92N14O9
1081.41
11.21
+6
3.68
-1.271
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
25 µM
Hemolytic Cytotoxic
50% Hemolysis | 25 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
De novo design of selective antibiotic peptides by incorporation of unnatural amino acids. | J Med Chem | 2007
Evidence 2 Activity

Activity

87% Hemolysis
Toxicity
100 µM
Hemolytic Cytotoxic
87% Hemolysis | 100 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
De novo design of selective antibiotic peptides by incorporation of unnatural amino acids. | J Med Chem | 2007