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Peptide record

TPDB19630

Antibacterial Antifungal Toxicity modified_plain modified
24 amino acids
Basic Information
3D PDB MODEL
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TPDB19630
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb dbAMP
modified_plain
Yes
A 24-aa modified multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, CAFPdb, and dbAMP, with an available 3D structural model.
Modified, details unspecified
Sequence
FXIXAXLGGCLGXFCGGIXAXLXF
Physicochemical Analysis
C79H119N17O18S2
RNDEQHKMPSTWYV
G
1659.04
5.18
0
0
10
-0
-6.46
1.475
89.58
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
125
7.53
2
Residue Composition
number
2
A
0
R
0
N
0
D
2
C
0
E
0
Q
5
G
0
H
2
I
3
L
0
K
0
M
3
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 5 H: 0 I: 2 L: 3 K: 0 M: 0 F: 3 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
24
C79H119N17O18S2
1659.04
5.18
-0
-6.46
1.475
Evidence Records 2 records
Evidence 1 Activity

Activity

10% Killing
Toxicity
143 µg/mL
Cytotoxic
10% Killing | 143 | µg/mL | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Designed Antimicrobial Peptides for Recurrent Vulvovaginal Candidiasis Treatment. | Antimicrob Agents Chemother | 2019
Evidence 2 Activity

Activity

<10% Killing
Toxicity
64 µg/mL
Cytotoxic
<10% Killing | 64 | µg/mL | target cell: Mouse fibroblasts L929

Target

Mouse fibroblasts L929

Source & Reference

NA
DBAASP
Designed Antimicrobial Peptides Against Trauma-Related Cutaneous Invasive Fungal Wound Infections. | J Fungi (Basel) | 2020