Peptide record

TPDB19620

Antibacterial Antifungal Hemolysis Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB19620
Antibacterial Antifungal Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb PD_Hemolysis
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Antifungal, Hemolysis, and other sources) peptide sequence curated from Peptipedia, CAFPdb, and PD_Hemolysis, with an available 3D structural model.
Sequence
FWSTIWNAAKSLI
Physicochemical Analysis
C75H109N17O18
RDCEQGHMPYV
AISW
1536.79
10.10
1
0
8
+1
-4.54
0.592
105.38
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
11000
715.78
4
Residue Composition
number
2
A
0
R
1
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
1
L
1
K
0
M
1
F
0
P
2
S
1
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 1 K: 1 M: 0 F: 1 P: 0 S: 2 T: 1 W: 2 Y: 0 V: 0
Chemical Descriptors
13
C75H109N17O18
1536.79
10.10
+1
-4.54
0.592
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
10.8±0.4 µM
Hemolytic Cytotoxic
50% Hemolysis | 10.8±0.4 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structural and functional characterization of NDBP-4 family antimicrobial peptides from the scorpion Mesomexovis variegatus. | Peptides | 2021
Evidence 2 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis