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Peptide record

TPDB19619

Antibacterial Antifungal standard
27 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB19619
Antibacterial Antifungal
Anti-infective peptides
Peptipedia AFP-GFuse Antifungipept CAFPdb DRAMP dbAMP
standard
No
A 27-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from Peptipedia, AFP-GFuse, Antifungipept, and other sources, with an available 3D structural model.
Sequence
FWSFLVKAASKILPSLIGGGDDNKSSS
Physicochemical Analysis
C129H202N32O39
RCEQHMTY
S
2825.21
9.76
3
2
11
+1
0.43
0.115
90.37
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
5500
194.68
7
Residue Composition
number
2
A
0
R
1
N
2
D
0
C
0
E
0
Q
3
G
0
H
2
I
3
L
3
K
0
M
2
F
1
P
6
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 2 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 2 L: 3 K: 3 M: 0 F: 2 P: 1 S: 6 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
27
C129H202N32O39
2825.21
9.76
+1
0.43
0.115
Evidence Records 12 records
Evidence 1 Activity

Activity

MIC
Antibacterial
100 µM

Target

Candida albicans SC5314

Source & Reference

dbAMP DRAMP

Other

Source Activity Label Source Definition
Antibacterial
DRAMP antibacterial activity supported by MIC records against bacterial target organisms. dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against C. albicans SC5314 (MIC 100 uM), C. tropicalis ATCC 750 (MIC 12.5 uM), C. parapsilosis ATCC 22019 (MIC 200 uM), C. glabra
Evidence 2 Activity

Activity

MIC
Antibacterial
12.5 µM

Target

C. tropicalis ATCC 750

Source & Reference

dbAMP DRAMP

Other

Active against C. albicans SC5314 (MIC 100 uM), C. tropicalis ATCC 750 (MIC 12.5 uM), C. parapsilosis ATCC 22019 (MIC 200 uM), C. glabrata ATCC 90030 (MIC 200 uM), C. neoform
Evidence 3 Activity

Activity

MIC
Antibacterial
200 µM

Target

C. parapsilosis ATCC 22019

Source & Reference

dbAMP DRAMP

Other

Active against C. albicans SC5314 (MIC 100 uM), C. tropicalis ATCC 750 (MIC 12.5 uM), C. parapsilosis ATCC 22019 (MIC 200 uM), C. glabrata ATCC 90030 (MIC 200 uM), C. neoformans H99 serotype A (MIC 50 uM), and C. ne
Evidence 4 Activity

Activity

MIC
Antibacterial
200 µM

Target

C. glabrata ATCC 90030

Source & Reference

dbAMP DRAMP

Other

C 100 uM), C. tropicalis ATCC 750 (MIC 12.5 uM), C. parapsilosis ATCC 22019 (MIC 200 uM), C. glabrata ATCC 90030 (MIC 200 uM), C. neoformans H99 serotype A (MIC 50 uM), and C. neoformans B3501 serotype D (MIC 25 uM)
Evidence 5 Activity

Activity

MIC
Antibacterial
50 µM

Target

C. neoformans H99 serotype A

Source & Reference

dbAMP DRAMP

Other

C 12.5 uM), C. parapsilosis ATCC 22019 (MIC 200 uM), C. glabrata ATCC 90030 (MIC 200 uM), C. neoformans H99 serotype A (MIC 50 uM), and C. neoformans B3501 serotype D (MIC 25 uM). The Con10 scorpion peptide inhibited the
Evidence 6 Activity

Activity

MIC
Antibacterial
25 µM

Target

C. neoformans B3501 serotype D

Source & Reference

dbAMP DRAMP

Other

0 uM), C. glabrata ATCC 90030 (MIC 200 uM), C. neoformans H99 serotype A (MIC 50 uM), and C. neoformans B3501 serotype D (MIC 25 uM). The Con10 scorpion peptide inhibited the biofilm formation of different A. baumannii in
Evidence 7 Activity

Activity

MIC
Antifungal
100 µM

Target

Candida albicans SC5314

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
DRAMP antifungal activity supported by activity records against fungal target organisms. dbAMP classified under the Anti-fungal function class.
Active against C. albicans SC5314 (MIC 100 uM), C. tropicalis ATCC 750 (MIC 12.5 uM), C. parapsilosis ATCC 22019 (MIC 200 uM), C. glabra
Evidence 8 Activity

Activity

MIC
Antifungal
12.5 µM

Target

C. tropicalis ATCC 750

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against C. albicans SC5314 (MIC 100 uM), C. tropicalis ATCC 750 (MIC 12.5 uM), C. parapsilosis ATCC 22019 (MIC 200 uM), C. glabrata ATCC 90030 (MIC 200 uM), C. neoform
Evidence 9 Activity

Activity

MIC
Antifungal
200 µM

Target

C. parapsilosis ATCC 22019

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

Active against C. albicans SC5314 (MIC 100 uM), C. tropicalis ATCC 750 (MIC 12.5 uM), C. parapsilosis ATCC 22019 (MIC 200 uM), C. glabrata ATCC 90030 (MIC 200 uM), C. neoformans H99 serotype A (MIC 50 uM), and C. ne
Evidence 10 Activity

Activity

MIC
Antifungal
200 µM

Target

C. glabrata ATCC 90030

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

C 100 uM), C. tropicalis ATCC 750 (MIC 12.5 uM), C. parapsilosis ATCC 22019 (MIC 200 uM), C. glabrata ATCC 90030 (MIC 200 uM), C. neoformans H99 serotype A (MIC 50 uM), and C. neoformans B3501 serotype D (MIC 25 uM)
Evidence 11 Activity

Activity

MIC
Antifungal
50 µM

Target

C. neoformans H99 serotype A

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

C 12.5 uM), C. parapsilosis ATCC 22019 (MIC 200 uM), C. glabrata ATCC 90030 (MIC 200 uM), C. neoformans H99 serotype A (MIC 50 uM), and C. neoformans B3501 serotype D (MIC 25 uM). The Con10 scorpion peptide inhibited the
Evidence 12 Activity

Activity

MIC
Antifungal
25 µM

Target

C. neoformans B3501 serotype D

Source & Reference

dbAMP DRAMP CAFPdb Antifungipept

Other

0 uM), C. glabrata ATCC 90030 (MIC 200 uM), C. neoformans H99 serotype A (MIC 50 uM), and C. neoformans B3501 serotype D (MIC 25 uM). The Con10 scorpion peptide inhibited the biofilm formation of different A. baumannii in