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Peptide record

TPDB19609

Antibacterial Toxicity modified_plain modified
5 amino acids
Basic Information
3D PDB MODEL
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TPDB19609
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 5-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
FWXRW
Physicochemical Analysis
C37H43N9O5
ANDCEQGHILKMPSTYV
W
693.81
11.05
1
0
3
+1
-4.02
-0.700
0.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
11000
1585.46
0
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
1
F
0
P
0
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 1 P: 0 S: 0 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
5
C37H43N9O5
693.81
11.05
+1
-4.02
-0.700
Evidence Records 1 records
Evidence 1 Activity

Activity

<10% Hemolysis
Toxicity
200 µM
Hemolytic Cytotoxic
<10% Hemolysis | 200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Arg/Trp-Rich Cyclic ?/?-Antimicrobial Peptides: The Roles of H-bonding and Hydrophobic/Hydrophilic Solvent Accessible Surface Areas upon the Activity and Membrane Selectivity. | Chemistry | 2018