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Peptide record

TPDB19593

Antibacterial Antiparasitic Toxicity standard
23 amino acids
Basic Information
3D PDB MODEL
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TPDB19593
Antibacterial Antiparasitic Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia ToxinPred 3.0
standard
No
A 23-aa standard natural multi-activity (Antibacterial, Antiparasitic, and Toxicity) peptide sequence curated from Peptipedia and ToxinPred 3.0, with an available 3D structural model.
Sequence
FWGAAAKMLGKALPGLISMFQKN
Physicochemical Analysis
C116H183N29O27S2
RDCEHTYV
A
2480.03
10.84
3
0
13
+3
-2.66
0.404
85.22
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
5500
221.77
3
Residue Composition
number
4
A
0
R
1
N
0
D
0
C
0
E
1
Q
3
G
0
H
1
I
3
L
3
K
2
M
2
F
1
P
1
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 4 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 1 G: 3 H: 0 I: 1 L: 3 K: 3 M: 2 F: 2 P: 1 S: 1 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
23
C116H183N29O27S2
2480.03
10.84
+3
-2.66
0.404
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
28.6-48.2 µM
Hemolytic Cytotoxic
50% Hemolysis | 28.6-48.2 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Multipurpose peptides: The venoms of Amazonian stinging ants contain anthelmintic ponericins with diverse predatory and defensive activities. | Biochem Pharmacol | 2021
Evidence 2 Activity

Activity

50% Cytotoxicity
Toxicity
12.6-13.5 µM
Cytotoxic
50% Cytotoxicity | 12.6-13.5 | µM | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Multipurpose peptides: The venoms of Amazonian stinging ants contain anthelmintic ponericins with diverse predatory and defensive activities. | Biochem Pharmacol | 2021