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Peptide record

TPDB19592

Antibacterial Antiviral Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB19592
Antibacterial Antiviral Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia AI4AVP dbAMP 3.0 DRAVP 2.0
standard
No
A 20-aa standard natural multi-activity (Antibacterial, Antiviral, and Toxicity) peptide sequence curated from Peptipedia, AI4AVP, dbAMP 3.0, and other sources, with an available 3D structural model.
Sequence
FWFTLIKTQAKQPARYRRFC
Physicochemical Analysis
C121H182N34O26S1
NDEGHMSV
RF
2561.05
11.41
5
0
9
+5
-1.33
-0.535
49.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
6990
272.94
6
Residue Composition
number
2
A
3
R
0
N
0
D
1
C
0
E
2
Q
0
G
0
H
1
I
1
L
2
K
0
M
3
F
1
P
0
S
2
T
1
W
1
Y
0
V
Amino Acid Distribution
A: 2 R: 3 N: 0 D: 0 C: 1 E: 0 Q: 2 G: 0 H: 0 I: 1 L: 1 K: 2 M: 0 F: 3 P: 1 S: 0 T: 2 W: 1 Y: 1 V: 0
Chemical Descriptors
20
C121H182N34O26S1
2561.05
11.41
+5
-1.33
-0.535
Evidence Records 2 records
Evidence 1 Activity

Activity

Toxicity
Cytotoxic
- | NA | target cell: Monkey kidney epithelial cells LLC-MK2

Target

Monkey kidney epithelial cells LLC-MK2

Source & Reference

NA
DBAASP
Structural optimization and de novo design of dengue virus entry inhibitory peptides. | PLoS Negl Trop Dis | 2010
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
Cytotoxicity: [Ref.20582308]the peptide showed no toxic to LLC-MK2 cells at 50 µM.

Source & Reference

NA
DRAMP
PLoS Negl Trop Dis. 2010 Jun 22 4(6):e721.