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Peptide record

TPDB19585

Antibacterial Antifungal Toxicity modified_plain modified
13 amino acids
Basic Information
3D PDB MODEL
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TPDB19585
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb
modified_plain
Yes
A 13-aa modified multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia and CAFPdb, with an available 3D structural model.
Modified, details unspecified
Sequence
FVXWFSKFLGRIL
Physicochemical Analysis
C78H113N17O14
ANDCEQHMPTY
F
1512.86
11.49
2
0
8
+2
-4.66
1.092
112.31
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
5500
363.55
1
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
1
I
2
L
1
K
0
M
3
F
0
P
1
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 2 K: 1 M: 0 F: 3 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
13
C78H113N17O14
1512.86
11.49
+2
-4.66
1.092
Evidence Records 3 records
Evidence 1 Activity

Activity

60% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
60% Hemolysis | 50 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
The Outcomes of Decorated Prolines in the Discovery of Antimicrobial Peptides from Temporin-L. | ChemMedChem | 2019
Evidence 2 Activity

Activity

35% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
35% Hemolysis | 50 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
The Outcomes of Decorated Prolines in the Discovery of Antimicrobial Peptides from Temporin-L. | ChemMedChem | 2019
Evidence 3 Activity

Activity

90% Hemolysis
Toxicity
50 µM
Hemolytic Cytotoxic
90% Hemolysis | 50 | µM | target cell: Sheep erythrocytes

Target

Sheep erythrocytes

Source & Reference

NA
DBAASP
The Outcomes of Decorated Prolines in the Discovery of Antimicrobial Peptides from Temporin-L. | ChemMedChem | 2019