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Peptide record

TPDB19583

Antibacterial Anticancer Hemolysis Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB19583
Antibacterial Anticancer Hemolysis Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia AntiCP 2.0 SATPdb dbACP iACP-DRLF pep-lab HemoPI Hemolytic2 PD_Hemolysis
standard
No
A 17-aa standard natural multi-activity (Antibacterial, Anticancer, Hemolysis, and other sources) peptide sequence curated from Peptipedia, AntiCP 2.0, SATPdb, and other sources, with an available 3D structural model.
Sequence
FVKLKKILNIILSIFKK
Physicochemical Analysis
C102H177N23O20
ARDCEQGHMPTWY
K
2045.67
11.12
5
0
10
+5
0.39
0.906
177.65
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
2
Residue Composition
number
0
A
0
R
1
N
0
D
0
C
0
E
0
Q
0
G
0
H
4
I
3
L
5
K
0
M
2
F
0
P
1
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 4 L: 3 K: 5 M: 0 F: 2 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
17
C102H177N23O20
2045.67
11.12
+5
0.39
0.906
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
28.34 µM
Hemolytic Cytotoxic
50% Hemolysis | 28.34 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Design of potent, non-toxic anticancer peptides based on the structure of the antimicrobial peptide, temporin-1CEa. | Arch Pharm Res | 2013
Evidence 2 Hemolysis

Source & Reference

HemoPI PD_Hemolysis
PD_Hemolysis