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Peptide record

TPDB19564

Antibacterial Antifungal Toxicity modified_plain modified
13 amino acids
Basic Information
3D PDB MODEL
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TPDB19564
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb dbAMP
modified_plain
Yes
A 13-aa modified multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, CAFPdb, and dbAMP, with an available 3D structural model.
Modified, details unspecified
Sequence
FVQWFSKFLGXIL
Physicochemical Analysis
C77H109N15O15
ARNDCEHMPTY
F
1484.80
10.10
1
0
8
+1
-4.89
1.169
112.31
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
5500
370.42
2
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
1
Q
1
G
0
H
1
I
2
L
1
K
0
M
3
F
0
P
1
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 1 H: 0 I: 1 L: 2 K: 1 M: 0 F: 3 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
13
C77H109N15O15
1484.80
10.10
+1
-4.89
1.169
Evidence Records 5 records
Evidence 1 Activity

Activity

89% Hemolysis
Toxicity
24 µM
Hemolytic Cytotoxic
89% Hemolysis | 24 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-activity relationship, conformational and biological studies of temporin L analogues. | J Med Chem | 2011
Evidence 2 Activity

Activity

62% Hemolysis
Toxicity
12 µM
Hemolytic Cytotoxic
62% Hemolysis | 12 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-activity relationship, conformational and biological studies of temporin L analogues. | J Med Chem | 2011
Evidence 3 Activity

Activity

22% Hemolysis
Toxicity
6 µM
Hemolytic Cytotoxic
22% Hemolysis | 6 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-activity relationship, conformational and biological studies of temporin L analogues. | J Med Chem | 2011
Evidence 4 Activity

Activity

7% Hemolysis
Toxicity
3 µM
Hemolytic Cytotoxic
7% Hemolysis | 3 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-activity relationship, conformational and biological studies of temporin L analogues. | J Med Chem | 2011
Evidence 5 Activity

Activity

3% Hemolysis
Toxicity
1.5 µM
Hemolytic Cytotoxic
3% Hemolysis | 1.5 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structure-activity relationship, conformational and biological studies of temporin L analogues. | J Med Chem | 2011