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Peptide record

TPDB19557

Antibacterial Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB19557
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 13-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
FVQWASKFLGRIL
Physicochemical Analysis
C77H117N19O16
NDCEHMPTY
LF
1564.89
11.49
2
0
8
+2
-3.12
0.746
120.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
5500
351.46
2
Residue Composition
number
1
A
1
R
0
N
0
D
0
C
0
E
1
Q
1
G
0
H
1
I
2
L
1
K
0
M
2
F
0
P
1
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 1 H: 0 I: 1 L: 2 K: 1 M: 0 F: 2 P: 0 S: 1 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
13
C77H117N19O16
1564.89
11.49
+2
-3.12
0.746
Evidence Records 2 records
Evidence 1 Activity

Activity

6.8% Hemolysis
Toxicity
24 µM
Hemolytic Cytotoxic
6.8% Hemolysis | 24 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Modulation of anti-endotoxin property of Temporin L by minor amino acid substitution in identified phenylalanine zipper sequence. | Biochem J | 2016
Evidence 2 Activity

Activity

27% Cytotoxicity
Toxicity
24 µM
Cytotoxic
27% Cytotoxicity | 24 | µM | target cell: Mouse fibroblasts NIH 3T3

Target

Mouse fibroblasts NIH 3T3

Source & Reference

NA
DBAASP
Modulation of anti-endotoxin property of Temporin L by minor amino acid substitution in identified phenylalanine zipper sequence. | Biochem J | 2016