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Peptide record

TPDB19544

Antibacterial Anticancer Antifungal Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB19544
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia AntiCP 2.0 SATPdb dbACP iACP-DRLF pep-lab dbAMP
standard
No
A 17-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from Peptipedia, AntiCP 2.0, SATPdb, and other sources, with an available 3D structural model.
Sequence
FVDLKKIANIINSIFKK
Physicochemical Analysis
C95H159N23O23
RCEQGHMPTWY
IK
1991.45
10.55
4
1
9
+3
2.00
0.382
137.65
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
3
Residue Composition
number
1
A
0
R
2
N
1
D
0
C
0
E
0
Q
0
G
0
H
4
I
1
L
4
K
0
M
2
F
0
P
1
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 2 D: 1 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 4 L: 1 K: 4 M: 0 F: 2 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
17
C95H159N23O23
1991.45
10.55
+3
2.00
0.382
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
1467 µM
Hemolytic Cytotoxic
50% Hemolysis | 1467 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Design of potent, non-toxic anticancer peptides based on the structure of the antimicrobial peptide, temporin-1CEa. | Arch Pharm Res | 2013