TPDB

3D PDB MODEL

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TPDB ID TPDB19542

Activity

Antibacterial

Activity_category_statistics

Anti-infective peptides

Database_Source

Peptipedia

Sequence_Type

standard

Has_Modification No

Description A 5-aa standard natural antibacterial peptide sequence curated from Peptipedia, with an available 3D structural model.

Sequence

FSTRF

FASTA

>TPDB19542|Antibacterial|length=5
FSTRF

Formula C31H44N8O8

Absent Amino Acids ANDCEQGHILKMPWYV

Common Amino Acids F

Mass 656.74

PI 11.05

Basic Residues 1

Acidic Residues 0

Hydrophobic Residues 2

Net Charge +1

Boman Index -1.18

Hydrophobicity -0.080

Aliphatic Index 0.00

Half Life

Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min

Extinction Coefficient Cystines 0

Absorbance 280nm 0.00

Polar Residues 2

number

0

A

1

R

0

N

0

D

0

C

0

E

0

Q

0

G

0

H

0

I

0

L

0

K

0

M

2

F

0

P

1

S

1

T

0

W

0

Y

0

V

Amino Acid Distribution

A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 2 P: 0 S: 1 T: 1 W: 0 Y: 0 V: 0

Length

5

Formula

C31H44N8O8

Mass

656.74

PI

11.05

Net Charge

+1

Boman Index

-1.18

Hydrophobicity

-0.080

Evidence 1 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 4 µg/mL

Target

Target Organism B. subtilis 168 1A1

Source & Reference

Database Source NA

Other

Evidence Text

active against B. subtilis 168 1A1 (MIC 4 ug/ml), E. faecium Com15 (MIC 8 ug/ml), S. aureus USA300 (MIC 4 ug/ml), E-coli DH5alpha (MIC>64

Evidence 2 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 8 µg/mL

Target

Target Organism E. faecium Com15

Source & Reference

Database Source NA

Other

Evidence Text

active against B. subtilis 168 1A1 (MIC 4 ug/ml), E. faecium Com15 (MIC 8 ug/ml), S. aureus USA300 (MIC 4 ug/ml), E-coli DH5alpha (MIC>64 ug/ml), K-pneumoniae ATCC 10031

Evidence 3 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 4 µg/mL

Target

Target Organism Staphylococcus aureus USA300

Source & Reference

Database Source NA

Other

Evidence Text

active against B. subtilis 168 1A1 (MIC 4 ug/ml), E. faecium Com15 (MIC 8 ug/ml), S. aureus USA300 (MIC 4 ug/ml), E-coli DH5alpha (MIC>64 ug/ml), K-pneumoniae ATCC 10031 (MIC>64 ug/ml), A. baumannii ATC

Evidence 4 Activity

Activity

Activity Endpoint MIC

Detail Source Activity Antibacterial

Activity Measurement 8 µg/mL

Target

Target Organism A. baumannii ATCC 17978

Source & Reference

Database Source NA

Other

Evidence Text

00 (MIC 4 ug/ml), E-coli DH5alpha (MIC>64 ug/ml), K-pneumoniae ATCC 10031 (MIC>64 ug/ml), A. baumannii ATCC 17978 (MIC 8 ug/ml), P-aeruginosa PAO1 (MIC>64 ug/ml), E-cloacae ATCC 14037 (MIC>64 ug/ml), M-tuberculosis H3