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Peptide record

TPDB19518

Antibacterial standard
34 amino acids
Basic Information
3D PDB MODEL
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TPDB19518
Antibacterial
Anti-infective peptides
Peptipedia
standard
No
A 34-aa standard natural antibacterial peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
FTSISMCTPGCKTGALMTCNYKTATCHCSIKVSK
Physicochemical Analysis
C151H251N41O47S7
RDEQW
T
3617.32
8.81
5
0
10
+4
1.99
0.185
48.82
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
1740
48.10
17
Residue Composition
number
2
A
0
R
1
N
0
D
5
C
0
E
0
Q
2
G
1
H
2
I
1
L
4
K
2
M
1
F
1
P
4
S
6
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 1 D: 0 C: 5 E: 0 Q: 0 G: 2 H: 1 I: 2 L: 1 K: 4 M: 2 F: 1 P: 1 S: 4 T: 6 W: 0 Y: 1 V: 1
Chemical Descriptors
34
C151H251N41O47S7
3617.32
8.81
+4
1.99
0.185
Evidence Records 4 records
Evidence 1 Activity

Activity

MIC
Antibacterial
0.19-0.78 µM

Target

Staphylococcus aureus ATCC 29213 MSSA or MRSA

Source & Reference

NA

Other

yointestinalis DPC6484 (0.32 cm2), and S. uberis strain 42 (2.38 cm2). MIC values against S. aureus ATCC 29213 MSSA or MRSA (MIC 0.19-0.78 uM), E. faecalis ATCC 29212 or 51299 VRE (MIC 1.56 uM), E. faecium ATCC 35667 or 700221 VRE (
Evidence 2 Activity

Activity

MIC
Antibacterial
1.56 µM

Target

Enterococcus faecalis ATCC 29212 or 51299 VRE

Source & Reference

NA

Other

n 42 (2.38 cm2). MIC values against S. aureus ATCC 29213 MSSA or MRSA (MIC 0.19-0.78 uM), E. faecalis ATCC 29212 or 51299 VRE (MIC 1.56 uM), E. faecium ATCC 35667 or 700221 VRE (MIC 0.39 uM) anti-VRE, and B. subtilis 168 (MIC 0.1
Evidence 3 Activity

Activity

MIC
Antibacterial
0.39 µM

Target

E. faecium ATCC 35667 or 700221 VRE

Source & Reference

NA

Other

29213 MSSA or MRSA (MIC 0.19-0.78 uM), E. faecalis ATCC 29212 or 51299 VRE (MIC 1.56 uM), E. faecium ATCC 35667 or 700221 VRE (MIC 0.39 uM) anti-VRE, and B. subtilis 168 (MIC 0.1 uM) ( Reiners et al., 2020 ). Antivirus: Nisin was
Evidence 4 Activity

Activity

MIC
Antibacterial
0.1 µM

Target

B. subtilis 168

Source & Reference

NA

Other

51299 VRE (MIC 1.56 uM), E. faecium ATCC 35667 or 700221 VRE (MIC 0.39 uM) anti-VRE, and B. subtilis 168 (MIC 0.1 uM) ( Reiners et al., 2020 ). Antivirus: Nisin was found to interact with the SARS-CoV-2 spik