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Peptide record

TPDB19489

Antibacterial Antiviral Toxicity standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB19489
Antibacterial Antiviral Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia AI4AVP dbAMP 3.0 DRAVP 2.0
standard
No
A 25-aa standard natural multi-activity (Antibacterial, Antiviral, and Toxicity) peptide sequence curated from Peptipedia, AI4AVP, dbAMP 3.0, and other sources, with an available 3D structural model.
Sequence
FRFKIKFRLKFRFKARFKFRAKFRA
Physicochemical Analysis
C165H255N49O26
NDCEQGHMPSTWYV
F
3341.15
13.11
12
0
13
+12
0.38
-0.572
43.20
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
3
A
6
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
1
L
6
K
0
M
8
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 3 R: 6 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 1 K: 6 M: 0 F: 8 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
25
C165H255N49O26
3341.15
13.11
+12
0.38
-0.572
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Cytotoxicity
Toxicity
3.81 µM
Cytotoxic
50% Cytotoxicity | 3.81 | µM | target cell: Feline kidney epithelial CRFK cells

Target

Feline kidney epithelial CRFK cells

Source & Reference

NA
DBAASP
Inhibitory activity of synthetic peptide antibiotics on feline immunodeficiency virus infectivity in vitro. | J Virol | 2002
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
Cytotoxicity: [Ref.12208971]CrFK cell:TC50=3.81 µM.

Source & Reference

NA
DRAMP
J Virol. 2002 Oct 76(19):9952-61.