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Peptide record

TPDB19455

Antibacterial Anticancer Toxicity standard
24 amino acids
Basic Information
3D PDB MODEL
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TPDB19455
Antibacterial Anticancer Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia CancerPPD 2.0
standard
No
A 24-aa standard natural multi-activity (Antibacterial, Anticancer, and Toxicity) peptide sequence curated from Peptipedia and CancerPPD 2.0, with an available 3D structural model.
Sequence
FKKLKKLFSKLWNWKRKKRRQRRR
Physicochemical Analysis
C154H260N54O28
ADCEGHIMPTYV
K
3316.10
13.11
14
0
7
+14
6.27
-2.117
48.75
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
11000
331.71
3
Residue Composition
number
0
A
6
R
1
N
0
D
0
C
0
E
1
Q
0
G
0
H
0
I
3
L
8
K
0
M
2
F
0
P
1
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 6 N: 1 D: 0 C: 0 E: 0 Q: 1 G: 0 H: 0 I: 0 L: 3 K: 8 M: 0 F: 2 P: 0 S: 1 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
24
C154H260N54O28
3316.10
13.11
+14
6.27
-2.117
Evidence Records 2 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
>500 µM
Hemolytic Cytotoxic
5% Hemolysis | >500 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
TAT Modification of Alpha-Helical Anticancer Peptides to Improve Specificity and Efficacy. | PLoS One | 2015
Evidence 2 Activity

Activity

MHC
Toxicity
500 µM
Hemolytic Cytotoxic
Hemolytic_activity: Human RBC: MHC>500 µM | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
PLoS One. 2015 Sep 25 10(9):e0138911.