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Peptide record

TPDB19433

Antibacterial Antiviral Toxicity standard
50 amino acids
Basic Information
3D PDB MODEL
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TPDB19433
Antibacterial Antiviral Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia AI4AVP dbAMP 3.0 DRAVP 2.0
standard
No
A 50-aa standard natural multi-activity (Antibacterial, Antiviral, and Toxicity) peptide sequence curated from Peptipedia, AI4AVP, dbAMP 3.0, and other sources, with an available 3D structural model.
Sequence
FNATYLNLTGEIDDLEFRSEKLHNTTVELAILIDNINNTLVNLEWLNRIE
Physicochemical Analysis
C261H412N68O84
CQMP
L
5846.55
4.02
4
9
22
-6
11.74
-0.164
124.80
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
6990
119.56
15
Residue Composition
number
2
A
2
R
8
N
3
D
0
C
6
E
0
Q
1
G
1
H
5
I
9
L
1
K
0
M
2
F
0
P
1
S
5
T
1
W
1
Y
2
V
Amino Acid Distribution
A: 2 R: 2 N: 8 D: 3 C: 0 E: 6 Q: 0 G: 1 H: 1 I: 5 L: 9 K: 1 M: 0 F: 2 P: 0 S: 1 T: 5 W: 1 Y: 1 V: 2
Chemical Descriptors
50
C261H412N68O84
5846.55
4.02
-6
11.74
-0.164
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Cell death
Toxicity
>=200 µM
Cytotoxic
50% Cell death | >=200 | µM | target cell: Fcwf-4 cells

Target

Fcwf-4 cells

Source & Reference

NA
DBAASP
Peptides corresponding to the predicted heptad repeat 2 domain of the feline coronavirus spike protein are potent inhibitors of viral infection. | PLoS One | 2013
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
Cytotoxicity: [Ref.24312629]Fcwf-4 cell:CC50>200 µM.

Source & Reference

NA
DRAMP
PLoS One. 2013 Dec 3 8(12):e82081.