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Peptide record

TPDB19431

Antibacterial Antiviral Toxicity standard
36 amino acids
Basic Information
3D PDB MODEL
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TPDB19431
Antibacterial Antiviral Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia AI4AVP dbAMP 3.0 DRAVP 2.0
standard
No
A 36-aa standard natural multi-activity (Antibacterial, Antiviral, and Toxicity) peptide sequence curated from Peptipedia, AI4AVP, dbAMP 3.0, and other sources, with an available 3D structural model.
Sequence
FNATYLNLTGEIDDLEFRSEKLHNTTVELAILIDNI
Physicochemical Analysis
C185H292N46O61
CQMPW
L
4136.62
3.96
3
7
16
-5
8.84
-0.033
121.94
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
1490
36.02
10
Residue Composition
number
2
A
1
R
4
N
3
D
0
C
4
E
0
Q
1
G
1
H
4
I
6
L
1
K
0
M
2
F
0
P
1
S
4
T
0
W
1
Y
1
V
Amino Acid Distribution
A: 2 R: 1 N: 4 D: 3 C: 0 E: 4 Q: 0 G: 1 H: 1 I: 4 L: 6 K: 1 M: 0 F: 2 P: 0 S: 1 T: 4 W: 0 Y: 1 V: 1
Chemical Descriptors
36
C185H292N46O61
4136.62
3.96
-5
8.84
-0.033
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Cell death
Toxicity
>=200 µM
Cytotoxic
50% Cell death | >=200 | µM | target cell: Fcwf-4 cells

Target

Fcwf-4 cells

Source & Reference

NA
DBAASP
Peptides corresponding to the predicted heptad repeat 2 domain of the feline coronavirus spike protein are potent inhibitors of viral infection. | PLoS One | 2013
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
Cytotoxicity: [Ref.24312629]Fcwf-4 cell:CC50>200 µM.

Source & Reference

NA
DRAMP
PLoS One. 2013 Dec 3 8(12):e82081.