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Peptide record

TPDB19429

Antibacterial Antiviral Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB19429
Antibacterial Antiviral Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia AI4AVP dbAMP 3.0
standard
No
A 22-aa standard natural multi-activity (Antibacterial, Antiviral, and Toxicity) peptide sequence curated from Peptipedia, AI4AVP, and dbAMP 3.0, with an available 3D structural model.
Sequence
FNATYLNLTGEIDDLEFRSEKL
Physicochemical Analysis
C116H178N28O39
CQHMPWV
L
2588.85
3.92
2
5
9
-3
5.66
-0.441
93.18
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
1490
57.55
6
Residue Composition
number
1
A
1
R
2
N
2
D
0
C
3
E
0
Q
1
G
0
H
1
I
4
L
1
K
0
M
2
F
0
P
1
S
2
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 1 R: 1 N: 2 D: 2 C: 0 E: 3 Q: 0 G: 1 H: 0 I: 1 L: 4 K: 1 M: 0 F: 2 P: 0 S: 1 T: 2 W: 0 Y: 1 V: 0
Chemical Descriptors
22
C116H178N28O39
2588.85
3.92
-3
5.66
-0.441
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Cell death
Toxicity
>=200 µM
Cytotoxic
50% Cell death | >=200 | µM | target cell: Fcwf-4 cells

Target

Fcwf-4 cells

Source & Reference

NA
DBAASP
Peptides corresponding to the predicted heptad repeat 2 domain of the feline coronavirus spike protein are potent inhibitors of viral infection. | PLoS One | 2013