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Peptide record

TPDB19422

Antibacterial Anticancer Antifungal Toxicity standard
17 amino acids
Basic Information
3D PDB MODEL
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TPDB19422
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia AntiCP 2.0 SATPdb dbACP iACP-DRLF pep-lab dbAMP
standard
No
A 17-aa standard natural multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from Peptipedia, AntiCP 2.0, SATPdb, and other sources, with an available 3D structural model.
Sequence
FKDLKKIANIINSIFKK
Physicochemical Analysis
C96H162N24O23
RCEQGHMPTWYV
K
2020.49
10.71
5
1
8
+4
2.92
-0.094
120.59
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
3
Residue Composition
number
1
A
0
R
2
N
1
D
0
C
0
E
0
Q
0
G
0
H
4
I
1
L
5
K
0
M
2
F
0
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 2 D: 1 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 4 L: 1 K: 5 M: 0 F: 2 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
17
C96H162N24O23
2020.49
10.71
+4
2.92
-0.094
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
1186 µM
Hemolytic Cytotoxic
50% Hemolysis | 1186 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Design of potent, non-toxic anticancer peptides based on the structure of the antimicrobial peptide, temporin-1CEa. | Arch Pharm Res | 2013