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Peptide record

TPDB19370

Antibacterial Antifungal Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB19370
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
FLQLIGRVLSGIL
Physicochemical Analysis
C68H117N17O16
ANDCEHKMPTWY
L
1428.78
11.05
1
0
8
+1
-2.38
1.662
202.31
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
2
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
1
Q
2
G
0
H
2
I
4
L
0
K
0
M
1
F
0
P
1
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 2 H: 0 I: 2 L: 4 K: 0 M: 0 F: 1 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
13
C68H117N17O16
1428.78
11.05
+1
-2.38
1.662
Evidence Records 4 records
Evidence 1 Activity

Activity

9% Hemolysis
Toxicity
3 µM
Hemolytic Cytotoxic
9% Hemolysis | 3 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A different molecular mechanism underlying antimicrobial and hemolytic actions of temporins A and L. | J Med Chem | 2008
Evidence 2 Activity

Activity

18% Hemolysis
Toxicity
6 µM
Hemolytic Cytotoxic
18% Hemolysis | 6 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A different molecular mechanism underlying antimicrobial and hemolytic actions of temporins A and L. | J Med Chem | 2008
Evidence 3 Activity

Activity

70% Hemolysis
Toxicity
12 µM
Hemolytic Cytotoxic
70% Hemolysis | 12 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A different molecular mechanism underlying antimicrobial and hemolytic actions of temporins A and L. | J Med Chem | 2008
Evidence 4 Activity

Activity

92% Hemolysis
Toxicity
24 µM
Hemolytic Cytotoxic
92% Hemolysis | 24 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
A different molecular mechanism underlying antimicrobial and hemolytic actions of temporins A and L. | J Med Chem | 2008