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Peptide record

TPDB19362

Antibacterial Toxicity standard
9 amino acids
Basic Information
3D PDB MODEL
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TPDB19362
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 9-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
FLKYLKKLL
Physicochemical Analysis
C60H100N12O11
ARNDCEQGHIMPSTWV
L
1165.53
10.46
3
0
6
+3
-1.34
0.556
173.33
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
1490
127.84
1
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
4
L
3
K
0
M
1
F
0
P
0
S
0
T
0
W
1
Y
0
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 4 K: 3 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 1 V: 0
Chemical Descriptors
9
C60H100N12O11
1165.53
10.46
+3
-1.34
0.556
Evidence Records 2 records
Evidence 1 Activity

Activity

<5% Hemolysis
Toxicity
16 µg/mL
Hemolytic Cytotoxic
<5% Hemolysis | 16 | µg/mL | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Feleucin-K3 Analogue with an α-(4-Pentenyl)-Ala Substitution at the Key Site Has More Potent Antimicrobial and Antibiofilm Activities in Vitro and in Vivo. | ACS Infect Dis | 2021
Evidence 2 Activity

Activity

7% Hemolysis
Toxicity
128 µg/mL
Hemolytic Cytotoxic
7% Hemolysis | 128 | µg/mL | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Feleucin-K3 Analogue with an α-(4-Pentenyl)-Ala Substitution at the Key Site Has More Potent Antimicrobial and Antibiofilm Activities in Vitro and in Vivo. | ACS Infect Dis | 2021