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Peptide record

TPDB19308

Antibacterial Hemolysis Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB19308
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia PD_Hemolysis ToxinPred 3.0
standard
No
A 13-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from Peptipedia, PD_Hemolysis, and ToxinPred 3.0, with an available 3D structural model.
Sequence
FLPLIAGLFGKIF
Physicochemical Analysis
C75H114N14O14
RNDCEQHMSTWYV
LF
1435.82
10.10
1
0
9
+1
-4.40
1.869
157.69
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
2
I
3
L
1
K
0
M
3
F
1
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 2 L: 3 K: 1 M: 0 F: 3 P: 1 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
13
C75H114N14O14
1435.82
10.10
+1
-4.40
1.869
Evidence Records 8 records
Evidence 1 Activity

Activity

MIC
Antibacterial
4 µM

Target

Staphylococcus aureus MRSA

Source & Reference

NA

Other

S. aureus MRSA (MIC 4 uM), E. faecalis (MIC 16 uM), E.coli (MIC >128 uM), P.aeruginosa (MIC >128 uM), K.pneumoniae
Evidence 2 Activity

Activity

MIC
Antibacterial
16 µM

Target

Enterococcus faecalis

Source & Reference

NA

Other

S. aureus MRSA (MIC 4 uM), E. faecalis (MIC 16 uM), E.coli (MIC >128 uM), P.aeruginosa (MIC >128 uM), K.pneumoniae (MIC >128 uM). MRSA biofi
Evidence 3 Activity

Activity

MIC
Antibacterial
>128 µM

Target

E.coli

Source & Reference

NA

Other

S. aureus MRSA (MIC 4 uM), E. faecalis (MIC 16 uM), E.coli (MIC >128 uM), P.aeruginosa (MIC >128 uM), K.pneumoniae (MIC >128 uM). MRSA biofilms (MBIC/MBEC 4/16 uM
Evidence 4 Activity

Activity

MIC
Antibacterial
>128 µM

Target

P.aeruginosa

Source & Reference

NA

Other

S. aureus MRSA (MIC 4 uM), E. faecalis (MIC 16 uM), E.coli (MIC >128 uM), P.aeruginosa (MIC >128 uM), K.pneumoniae (MIC >128 uM). MRSA biofilms (MBIC/MBEC 4/16 uM)
Evidence 5 Activity

Activity

MIC
Antibacterial
>128 µM

Target

K.pneumoniae

Source & Reference

NA

Other

SA (MIC 4 uM), E. faecalis (MIC 16 uM), E.coli (MIC >128 uM), P.aeruginosa (MIC >128 uM), K.pneumoniae (MIC >128 uM). MRSA biofilms (MBIC/MBEC 4/16 uM)
Evidence 6 Activity

Activity

30% Hemolysis
Toxicity
64 µM
Hemolytic Cytotoxic
30% Hemolysis | 64 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Aggregation and Its Influence on the Bioactivities of a Novel Antimicrobial Peptide, Temporin-PF, and Its Analogues. | Int J Mol Sci | 2021
Evidence 7 Activity

Activity

70% Hemolysis
Toxicity
128 µM
Hemolytic Cytotoxic
70% Hemolysis | 128 | µM | target cell: Horse erythrocytes

Target

Horse erythrocytes

Source & Reference

NA
DBAASP
Aggregation and Its Influence on the Bioactivities of a Novel Antimicrobial Peptide, Temporin-PF, and Its Analogues. | Int J Mol Sci | 2021
Evidence 8 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis