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Peptide record

TPDB19277

Antibacterial Toxicity standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB19277
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 13-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
FLPIVAELLSGLL
Physicochemical Analysis
C68H113N13O17
RNDCQHKMTWY
L
1384.72
3.29
0
1
9
-1
-1.73
2.000
210.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
1
A
0
R
0
N
0
D
0
C
1
E
0
Q
1
G
0
H
1
I
5
L
0
K
0
M
1
F
1
P
1
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 0 C: 0 E: 1 Q: 0 G: 1 H: 0 I: 1 L: 5 K: 0 M: 0 F: 1 P: 1 S: 1 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
13
C68H113N13O17
1384.72
3.29
-1
-1.73
2.000
Evidence Records 1 records
Evidence 1 Activity

Activity

10% Hemolysis
Toxicity
>256 µM
Hemolytic Cytotoxic
10% Hemolysis | >256 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Improving the Antimicrobial Performance of Amphiphilic Cationic Antimicrobial Peptides Using Glutamic Acid Full-Scan and Positive Charge Compensation Strategies. | J Med Chem | 2022