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Peptide record

TPDB19268

Antibacterial Anticancer Antifungal Toxicity modified_plain modified
24 amino acids
Basic Information
3D PDB MODEL
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TPDB19268
Antibacterial Anticancer Antifungal Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia CAFPdb dbAMP
modified_plain
Yes
A 24-aa modified multi-activity (Antibacterial, Anticancer, Antifungal, and other sources) peptide sequence curated from Peptipedia, CAFPdb, and dbAMP, with an available 3D structural model.
Modified, details unspecified
Sequence
FLPILASLAAKFGPKLFXLVTKKX
Physicochemical Analysis
C120H196N26O25
RNDCEQHMWY
L
2403.04
11.00
4
0
13
+4
-1.80
0.867
122.08
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
2
Residue Composition
number
3
A
0
R
0
N
0
D
0
C
0
E
0
Q
1
G
0
H
1
I
5
L
4
K
0
M
3
F
2
P
1
S
1
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 3 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 1 L: 5 K: 4 M: 0 F: 3 P: 2 S: 1 T: 1 W: 0 Y: 0 V: 1
Chemical Descriptors
24
C120H196N26O25
2403.04
11.00
+4
-1.80
0.867
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
4 µM
Hemolytic Cytotoxic
50% Hemolysis | 4 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Synthesis, conformational analysis and biological properties of a dicarba derivative of the antimicrobial peptide, brevinin-1BYa. | Eur Biophys J | 2011
Evidence 2 Activity

Activity

LC50
Toxicity
4 µM
Hemolytic Cytotoxic
Hemolytic_activity: Human erythrocytes: LC50=4 µM | Cytotoxicity: Not available

Target

erythrocytes

Source & Reference

NA
DRAMP
Eur Biophys J. 2011 Apr 40(4):555-64.