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Peptide record

TPDB19234

Antibacterial Antifungal Toxicity standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB19234
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 12-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
FLKLIWKRKKKK
Physicochemical Analysis
C80H138N22O13
ANDCEQGHMPSTYV
K
1616.12
11.90
7
0
5
+7
2.34
-1.158
97.50
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
5500
340.32
0
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
2
L
6
K
0
M
1
F
0
P
0
S
0
T
1
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 2 K: 6 M: 0 F: 1 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 0
Chemical Descriptors
12
C80H138N22O13
1616.12
11.90
+7
2.34
-1.158
Evidence Records 1 records
Evidence 1 Activity

Activity

5% Hemolysis
Toxicity
15.92 ± 0.55 µg/mL
Hemolytic Cytotoxic
5% Hemolysis | 15.92 ± 0.55 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Rational design, synthesis, antifungal evaluation and docking studies of antifungal peptide CGA-N12 analogues based on the target CtKRE9. | Bioorg Chem | 2023