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Peptide record

TPDB19230

Antibacterial Toxicity standard
27 amino acids
Basic Information
3D PDB MODEL
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TPDB19230
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia ToxinPred 3.0
standard
No
A 27-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia and ToxinPred 3.0, with an available 3D structural model.
Sequence
FLKHIKSFWRGAKAIFRGARQGWREHR
Physicochemical Analysis
C155H236N52O32
NDCMPTYV
R
3339.91
12.59
10
1
11
+7
2.92
-0.919
54.44
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
11000
329.35
2
Residue Composition
number
3
A
5
R
0
N
0
D
0
C
1
E
1
Q
3
G
2
H
2
I
1
L
3
K
0
M
3
F
0
P
1
S
0
T
2
W
0
Y
0
V
Amino Acid Distribution
A: 3 R: 5 N: 0 D: 0 C: 0 E: 1 Q: 1 G: 3 H: 2 I: 2 L: 1 K: 3 M: 0 F: 3 P: 0 S: 1 T: 0 W: 2 Y: 0 V: 0
Chemical Descriptors
27
C155H236N52O32
3339.91
12.59
+7
2.92
-0.919
Evidence Records 18 records
Evidence 1 Activity

Activity

MIC
Antibacterial
11.23 µM

Target

V. alginolyticus

Source & Reference

NA

Other

active against Gram- bacteria V. alginolyticus (MIC 11.23 uM), V. anguillarum (MIC 11.23 uM), V. brasiliensis (MIC 2.81 uM), V. cholerae (MIC 5.61 uM),
Evidence 2 Activity

Activity

MIC
Antibacterial
11.23 µM

Target

V. anguillarum

Source & Reference

NA

Other

active against Gram- bacteria V. alginolyticus (MIC 11.23 uM), V. anguillarum (MIC 11.23 uM), V. brasiliensis (MIC 2.81 uM), V. cholerae (MIC 5.61 uM), V. fluvialis (MIC 11.23 uM), V
Evidence 3 Activity

Activity

MIC
Antibacterial
2.81 µM

Target

V. brasiliensis

Source & Reference

NA

Other

ve against Gram- bacteria V. alginolyticus (MIC 11.23 uM), V. anguillarum (MIC 11.23 uM), V. brasiliensis (MIC 2.81 uM), V. cholerae (MIC 5.61 uM), V. fluvialis (MIC 11.23 uM), V. harveyi (MIC 2.81 uM), V. par
Evidence 4 Activity

Activity

MIC
Antibacterial
5.61 µM

Target

V. cholerae

Source & Reference

NA

Other

ginolyticus (MIC 11.23 uM), V. anguillarum (MIC 11.23 uM), V. brasiliensis (MIC 2.81 uM), V. cholerae (MIC 5.61 uM), V. fluvialis (MIC 11.23 uM), V. harveyi (MIC 2.81 uM), V. parahaemolyticus (MIC 2.81 uM)
Evidence 5 Activity

Activity

MIC
Antibacterial
11.23 µM

Target

V. fluvialis

Source & Reference

NA

Other

V. anguillarum (MIC 11.23 uM), V. brasiliensis (MIC 2.81 uM), V. cholerae (MIC 5.61 uM), V. fluvialis (MIC 11.23 uM), V. harveyi (MIC 2.81 uM), V. parahaemolyticus (MIC 2.81 uM), V. plendidus (MIC 2.81 uM),
Evidence 6 Activity

Activity

MIC
Antibacterial
2.81 µM

Target

V. harveyi

Source & Reference

NA

Other

), V. brasiliensis (MIC 2.81 uM), V. cholerae (MIC 5.61 uM), V. fluvialis (MIC 11.23 uM), V. harveyi (MIC 2.81 uM), V. parahaemolyticus (MIC 2.81 uM), V. plendidus (MIC 2.81 uM), V. vulnificus (MIC 5.61 u
Evidence 7 Activity

Activity

MIC
Antibacterial
2.81 µM

Target

V. parahaemolyticus

Source & Reference

NA

Other

81 uM), V. cholerae (MIC 5.61 uM), V. fluvialis (MIC 11.23 uM), V. harveyi (MIC 2.81 uM), V. parahaemolyticus (MIC 2.81 uM), V. plendidus (MIC 2.81 uM), V. vulnificus (MIC 5.61 uM), A. hydrophila (MIC 5.61 uM), A.
Evidence 8 Activity

Activity

MIC
Antibacterial
2.81 µM

Target

V. plendidus

Source & Reference

NA

Other

V. fluvialis (MIC 11.23 uM), V. harveyi (MIC 2.81 uM), V. parahaemolyticus (MIC 2.81 uM), V. plendidus (MIC 2.81 uM), V. vulnificus (MIC 5.61 uM), A. hydrophila (MIC 5.61 uM), A. sobria (MIC 5.61 uM), A. ve
Evidence 9 Activity

Activity

MIC
Antibacterial
5.61 µM

Target

V. vulnificus

Source & Reference

NA

Other

V. harveyi (MIC 2.81 uM), V. parahaemolyticus (MIC 2.81 uM), V. plendidus (MIC 2.81 uM), V. vulnificus (MIC 5.61 uM), A. hydrophila (MIC 5.61 uM), A. sobria (MIC 5.61 uM), A. veronii (MIC 5.61 uM), Gram+ S.
Evidence 10 Activity

Activity

MIC
Antibacterial
5.61 µM

Target

A. hydrophila

Source & Reference

NA

Other

parahaemolyticus (MIC 2.81 uM), V. plendidus (MIC 2.81 uM), V. vulnificus (MIC 5.61 uM), A. hydrophila (MIC 5.61 uM), A. sobria (MIC 5.61 uM), A. veronii (MIC 5.61 uM), Gram+ S. aureus ATCC25923 or CMCC2600
Evidence 11 Activity

Activity

MIC
Antibacterial
5.61 µM

Target

A. sobria

Source & Reference

NA

Other

M), V. plendidus (MIC 2.81 uM), V. vulnificus (MIC 5.61 uM), A. hydrophila (MIC 5.61 uM), A. sobria (MIC 5.61 uM), A. veronii (MIC 5.61 uM), Gram+ S. aureus ATCC25923 or CMCC26003 (MIC 2.81-5.61 uM), and
Evidence 12 Activity

Activity

MIC
Antibacterial
5.61 µM

Target

A. veronii

Source & Reference

NA

Other

1 uM), V. vulnificus (MIC 5.61 uM), A. hydrophila (MIC 5.61 uM), A. sobria (MIC 5.61 uM), A. veronii (MIC 5.61 uM), Gram+ S. aureus ATCC25923 or CMCC26003 (MIC 2.81-5.61 uM), and N. asteroides (MIC 5.61 u
Evidence 13 Activity

Activity

MIC
Antibacterial
2.81-5.61 µM

Target

Staphylococcus aureus ATCC25923 or CMCC26003

Source & Reference

NA

Other

M), A. hydrophila (MIC 5.61 uM), A. sobria (MIC 5.61 uM), A. veronii (MIC 5.61 uM), Gram+ S. aureus ATCC25923 or CMCC26003 (MIC 2.81-5.61 uM), and N. asteroides (MIC 5.61 uM). Antibiofilm: inhibited biofilm formation: V. vulnificus
Evidence 14 Activity

Activity

MIC
Antibacterial
5.61 µM

Target

N. asteroides

Source & Reference

NA

Other

A. veronii (MIC 5.61 uM), Gram+ S. aureus ATCC25923 or CMCC26003 (MIC 2.81-5.61 uM), and N. asteroides (MIC 5.61 uM). Antibiofilm: inhibited biofilm formation: V. vulnificus:48h:0.5MIC:30%CV inhibited biof
Evidence 15 Activity

Activity

10.33% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
10.33% Hemolysis | 200 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Defensing role of novel piscidins from largemouth bass (Micropterus salmoides) with evidence of bactericidal activities and inducible expressional delineation. | Microbiol Res | 2022
Evidence 16 Activity

Activity

11.53% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
11.53% Hemolysis | 200 | µg/mL | target cell: Fish erythrocytes

Target

Fish erythrocytes

Source & Reference

NA
DBAASP
Defensing role of novel piscidins from largemouth bass (Micropterus salmoides) with evidence of bactericidal activities and inducible expressional delineation. | Microbiol Res | 2022
Evidence 17 Activity

Activity

25.57% Killing
Toxicity
200 µg/mL
Cytotoxic
25.57% Killing | 200 | µg/mL | target cell: Fathead minnow muscle cells (FHM)

Target

Fathead minnow muscle cells (FHM)

Source & Reference

NA
DBAASP
Defensing role of novel piscidins from largemouth bass (Micropterus salmoides) with evidence of bactericidal activities and inducible expressional delineation. | Microbiol Res | 2022
Evidence 18 Activity

Activity

24.34% Killing
Toxicity
200 µg/mL
Cytotoxic
24.34% Killing | 200 | µg/mL | target cell: Epithelioma papulosum cyprini cells (EPC)

Target

Epithelioma papulosum cyprini cells (EPC)

Source & Reference

NA
DBAASP
Defensing role of novel piscidins from largemouth bass (Micropterus salmoides) with evidence of bactericidal activities and inducible expressional delineation. | Microbiol Res | 2022