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Peptide record

TPDB19201

Antibacterial Anticancer standard
27 amino acids
Basic Information
3D PDB MODEL
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TPDB19201
Antibacterial Anticancer
Anti-infective peptides Cancer-related peptides
Peptipedia CancerPPD 2.0 dbACP
standard
No
A 27-aa standard natural multi-activity (Antibacterial and Anticancer) peptide sequence curated from Peptipedia, CancerPPD 2.0, and dbACP, with an available 3D structural model.
Sequence
FLGVALKLGKVLGKALLPLASSLLHSQ
Physicochemical Analysis
C131H225N33O32
RNDCEIMTWY
L
2774.43
10.84
4
0
15
+3
-1.16
1.007
162.59
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
4
Residue Composition
number
3
A
0
R
0
N
0
D
0
C
0
E
1
Q
3
G
1
H
0
I
9
L
3
K
0
M
1
F
1
P
3
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 3 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 1 G: 3 H: 1 I: 0 L: 9 K: 3 M: 0 F: 1 P: 1 S: 3 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
27
C131H225N33O32
2774.43
10.84
+3
-1.16
1.007
Evidence Records 6 records
Evidence 1 Activity

Activity

MIC
Antibacterial
7.8 µM

Target

Staphylococcus aureus ATCC 12600

Source & Reference

NA

Other

active against Gram+ S. aureus ATCC 12600 (MIC 7.8 uM), E. faecium ATCC 19439 (MIC 31.3 uM), E.faecalis ATCC 51299 (MIC 125 uM), Gram- E. coli A
Evidence 2 Activity

Activity

MIC
Antibacterial
31.3 µM

Target

E. faecium ATCC 19439

Source & Reference

NA

Other

active against Gram+ S. aureus ATCC 12600 (MIC 7.8 uM), E. faecium ATCC 19439 (MIC 31.3 uM), E.faecalis ATCC 51299 (MIC 125 uM), Gram- E. coli ATCC 35218 (MIC 15.6 uM), K. pneumonia
Evidence 3 Activity

Activity

MIC
Antibacterial
125 µM

Target

Enterococcus faecalis ATCC 51299

Source & Reference

NA

Other

ive against Gram+ S. aureus ATCC 12600 (MIC 7.8 uM), E. faecium ATCC 19439 (MIC 31.3 uM), E.faecalis ATCC 51299 (MIC 125 uM), Gram- E. coli ATCC 35218 (MIC 15.6 uM), K. pneumoniae ATCC 49472 (MIC 31.3 uM), and P. a
Evidence 4 Activity

Activity

MIC
Antibacterial
15.6 µM

Target

Escherichia coli ATCC 35218

Source & Reference

NA

Other

C 7.8 uM), E. faecium ATCC 19439 (MIC 31.3 uM), E.faecalis ATCC 51299 (MIC 125 uM), Gram- E. coli ATCC 35218 (MIC 15.6 uM), K. pneumoniae ATCC 49472 (MIC 31.3 uM), and P. aeruginosa ATCC 9072 (MIC 31.3 uM). Also
Evidence 5 Activity

Activity

MIC
Antibacterial
31.3 µM

Target

Klebsiella pneumoniae ATCC 49472

Source & Reference

NA

Other

MIC 31.3 uM), E.faecalis ATCC 51299 (MIC 125 uM), Gram- E. coli ATCC 35218 (MIC 15.6 uM), K. pneumoniae ATCC 49472 (MIC 31.3 uM), and P. aeruginosa ATCC 9072 (MIC 31.3 uM). Also showed cytotoxicity to cancer cells ung
Evidence 6 Activity

Activity

MIC
Antibacterial
31.3 µM

Target

Pseudomonas aeruginosa ATCC 9072

Source & Reference

NA

Other

uM), Gram- E. coli ATCC 35218 (MIC 15.6 uM), K. pneumoniae ATCC 49472 (MIC 31.3 uM), and P. aeruginosa ATCC 9072 (MIC 31.3 uM). Also showed cytotoxicity to cancer cells ung adenocarcinoma A549 (LC50 6.7 uM), breast a