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Peptide record

TPDB19188

Antibacterial Hemolysis Toxicity standard
24 amino acids
Basic Information
3D PDB MODEL
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TPDB19188
Antibacterial Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia PD_Hemolysis ToxinPred 3.0
standard
No
A 24-aa standard natural multi-activity (Antibacterial, Hemolysis, and Toxicity) peptide sequence curated from Peptipedia, PD_Hemolysis, and ToxinPred 3.0, with an available 3D structural model.
Sequence
FLGALLKIGAKVLPSVLCGIFKKC
Physicochemical Analysis
C120H204N28O26S2
RNDEQHMTWY
L
2519.23
10.17
4
0
13
+4
-1.79
1.308
146.25
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
125
4.96
3
Residue Composition
number
2
A
0
R
0
N
0
D
2
C
0
E
0
Q
3
G
0
H
2
I
5
L
4
K
0
M
2
F
1
P
1
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 2 E: 0 Q: 0 G: 3 H: 0 I: 2 L: 5 K: 4 M: 0 F: 2 P: 1 S: 1 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
24
C120H204N28O26S2
2519.23
10.17
+4
-1.79
1.308
Evidence Records 5 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
16.62 µM
Hemolytic Cytotoxic
50% Hemolysis | 16.62 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Functional characterization of two novel peptides and their analogs identifed from the skin secretion of Indosylvirana aurantiaca, an endemic frog species of Western Ghats, India | Chemoecology | 2019
Evidence 2 Activity

Activity

LD50
Toxicity
15.39 µM
Cytotoxic
LD50 | 15.39 | µM | target cell: Human PBMC

Target

Human PBMC

Source & Reference

NA
DBAASP
Functional characterization of two novel peptides and their analogs identifed from the skin secretion of Indosylvirana aurantiaca, an endemic frog species of Western Ghats, India | Chemoecology | 2019
Evidence 3 Activity

Activity

50% Hemolysis
Toxicity
16.63 µM
Hemolytic Cytotoxic
50% Hemolysis | 16.63 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Functional characterization of two novel peptides and their analogs identifed from the skin secretion of Indosylvirana aurantiaca, an endemic frog species of Western Ghats, India | Chemoecology | 2019
Evidence 4 Activity

Activity

LD50
Toxicity
13.37 µM
Cytotoxic
LD50 | 13.37 | µM | target cell: Human PBMC

Target

Human PBMC

Source & Reference

NA
DBAASP
Functional characterization of two novel peptides and their analogs identifed from the skin secretion of Indosylvirana aurantiaca, an endemic frog species of Western Ghats, India | Chemoecology | 2019
Evidence 5 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis