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Peptide record

TPDB19187

Antibacterial Antifungal Antiparasitic Toxicity standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB19187
Antibacterial Antifungal Antiparasitic Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb ToxinPred 3.0
standard
No
A 25-aa standard natural multi-activity (Antibacterial, Antifungal, Antiparasitic, and other sources) peptide sequence curated from Peptipedia, CAFPdb, and ToxinPred 3.0, with an available 3D structural model.
Sequence
FLGALLKIGAKLLPSVVGLFKKKQQ
Physicochemical Analysis
C130H222N32O29
RNDCEHMTWY
L
2697.39
11.12
5
0
13
+5
0.59
0.592
140.40
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
3
Residue Composition
number
2
A
0
R
0
N
0
D
0
C
0
E
2
Q
3
G
0
H
1
I
6
L
5
K
0
M
2
F
1
P
1
S
0
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 2 G: 3 H: 0 I: 1 L: 6 K: 5 M: 0 F: 2 P: 1 S: 1 T: 0 W: 0 Y: 0 V: 2
Chemical Descriptors
25
C130H222N32O29
2697.39
11.12
+5
0.59
0.592
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
39.9-61.5 µM
Hemolytic Cytotoxic
50% Hemolysis | 39.9-61.5 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Multipurpose peptides: The venoms of Amazonian stinging ants contain anthelmintic ponericins with diverse predatory and defensive activities. | Biochem Pharmacol | 2021
Evidence 2 Activity

Activity

50% Cytotoxicity
Toxicity
4.5-5.9 µM
Cytotoxic
50% Cytotoxicity | 4.5-5.9 | µM | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Multipurpose peptides: The venoms of Amazonian stinging ants contain anthelmintic ponericins with diverse predatory and defensive activities. | Biochem Pharmacol | 2021