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Peptide record

TPDB19172

Antibacterial Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB19172
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 18-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
FLFSAGKAIHRLIRRRRR
Physicochemical Analysis
C101H173N39O20
NDCEQMPTWYV
R
2253.73
13.10
8
0
8
+7
2.61
-0.528
97.78
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
2
A
6
R
0
N
0
D
0
C
0
E
0
Q
1
G
1
H
2
I
2
L
1
K
0
M
2
F
0
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 6 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 1 H: 1 I: 2 L: 2 K: 1 M: 0 F: 2 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
18
C101H173N39O20
2253.73
13.10
+7
2.61
-0.528
Evidence Records 1 records
Evidence 1 Activity

Activity

2.02% Hemolysis
Toxicity
64 µg/mL
Hemolytic Cytotoxic
2.02% Hemolysis | 64 | µg/mL | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Rational design and synthesis of Oreoch-2 analogues as efficient broad-spectrum antimicrobial peptides | Bioorg Chem | 2021