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Peptide record

TPDB19158

Antibacterial Antifungal Toxicity standard
18 amino acids
Basic Information
3D PDB MODEL
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TPDB19158
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 18-aa standard natural multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
FKWKSVLKGVKGFVKGYF
Physicochemical Analysis
C107H160N24O21
ARNDCEQHIMPT
K
2118.60
10.77
5
0
9
+5
-1.42
0.061
70.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
6990
329.94
2
Residue Composition
number
0
A
0
R
0
N
0
D
0
C
0
E
0
Q
3
G
0
H
0
I
1
L
5
K
0
M
3
F
0
P
1
S
0
T
1
W
1
Y
3
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 0 I: 0 L: 1 K: 5 M: 0 F: 3 P: 0 S: 1 T: 0 W: 1 Y: 1 V: 3
Chemical Descriptors
18
C107H160N24O21
2118.60
10.77
+5
-1.42
0.061
Evidence Records 2 records
Evidence 1 Activity

Activity

26.5 ± 2.6% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
26.5 ± 2.6% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Strategic modification of low-activity natural antimicrobial peptides confers antibacterial potential in vitro and in vivo. | Eur J Med Chem | 2023
Evidence 2 Activity

Activity

LD50
Toxicity
>100 µg/mL
Cytotoxic
LD50 | >100 | µg/mL | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Strategic modification of low-activity natural antimicrobial peptides confers antibacterial potential in vitro and in vivo. | Eur J Med Chem | 2023