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Peptide record

TPDB19110

Antibacterial Toxicity standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB19110
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 22-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
FIIGGLFSAGKAIHRLIRRRRR
Physicochemical Analysis
C117H201N43O24
NDCEQMPTWYV
R
2594.16
13.10
8
0
10
+7
2.01
-0.059
115.45
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
2
A
6
R
0
N
0
D
0
C
0
E
0
Q
3
G
1
H
4
I
2
L
1
K
0
M
2
F
0
P
1
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 2 R: 6 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 1 I: 4 L: 2 K: 1 M: 0 F: 2 P: 0 S: 1 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
22
C117H201N43O24
2594.16
13.10
+7
2.01
-0.059
Evidence Records 1 records
Evidence 1 Activity

Activity

4.84% Hemolysis
Toxicity
64 µg/mL
Hemolytic Cytotoxic
4.84% Hemolysis | 64 | µg/mL | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Rational design and synthesis of Oreoch-2 analogues as efficient broad-spectrum antimicrobial peptides | Bioorg Chem | 2021