Back to search

Peptide record

TPDB19078

Antibacterial Toxicity standard
20 amino acids
Basic Information
3D PDB MODEL
Drag to rotate. Click a residue or atom to inspect it; the selected residue is highlighted in amber.
TPDB19078
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia ToxinPred 3.0
standard
No
A 20-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia and ToxinPred 3.0, with an available 3D structural model.
Sequence
FIGAALGALTAIPSIIKLFK
Physicochemical Analysis
C100H166N22O23
RNDCEQHMWYV
AI
2044.55
10.60
2
0
13
+2
-3.14
1.525
156.50
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
2
Residue Composition
number
4
A
0
R
0
N
0
D
0
C
0
E
0
Q
2
G
0
H
4
I
3
L
2
K
0
M
2
F
1
P
1
S
1
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 4 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 4 L: 3 K: 2 M: 0 F: 2 P: 1 S: 1 T: 1 W: 0 Y: 0 V: 0
Chemical Descriptors
20
C100H166N22O23
2044.55
10.60
+2
-3.14
1.525
Evidence Records 5 records
Evidence 1 Activity

Activity

IC50
Toxicity
12.55±0.28 µM
Cytotoxic
IC50 | 12.55±0.28 | µM | target cell: Human pancreas epithelial cells HPNE

Target

Human pancreas epithelial cells HPNE

Source & Reference

NA
DBAASP
Discovery of anticancer peptides from natural and generated sequences using deep learning. | Int J Biol Macromol | 2025
Evidence 2 Activity

Activity

IC50
Toxicity
19.13±0.77 µM
Cytotoxic
IC50 | 19.13±0.77 | µM | target cell: Human umbilical vein endothelial cells HUVEC

Target

Human umbilical vein endothelial cells HUVEC

Source & Reference

NA
DBAASP
Discovery of anticancer peptides from natural and generated sequences using deep learning. | Int J Biol Macromol | 2025
Evidence 3 Activity

Activity

IC50
Toxicity
14.09±0.59 µM
Cytotoxic
IC50 | 14.09±0.59 | µM | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Discovery of anticancer peptides from natural and generated sequences using deep learning. | Int J Biol Macromol | 2025
Evidence 4 Activity

Activity

IC50
Toxicity
37.38±7.27 µM
Cytotoxic
IC50 | 37.38±7.27 | µM | target cell: Human embryonic kidney HEK293T cells

Target

Human embryonic kidney HEK293T cells

Source & Reference

NA
DBAASP
Discovery of anticancer peptides from natural and generated sequences using deep learning. | Int J Biol Macromol | 2025
Evidence 5 Activity

Activity

50% Hemolysis
Toxicity
25 µM
Hemolytic Cytotoxic
50% Hemolysis | 25 | µM | target cell: Mouse erythrocytes

Target

Mouse erythrocytes

Source & Reference

NA
DBAASP
Discovery of anticancer peptides from natural and generated sequences using deep learning. | Int J Biol Macromol | 2025