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Peptide record

TPDB19076

Antibacterial Toxicity standard
25 amino acids
Basic Information
3D PDB MODEL
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TPDB19076
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia ToxinPred 3.0
standard
No
A 25-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia and ToxinPred 3.0, with an available 3D structural model.
Sequence
FIFHVIKGLFHAGKMIHGLVTRRRH
Physicochemical Analysis
C139H220N44O27S1
NDCEQPSWY
H
2971.61
12.71
9
0
12
+5
2.72
0.224
105.20
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
1
Residue Composition
number
1
A
3
R
0
N
0
D
0
C
0
E
0
Q
3
G
4
H
3
I
2
L
2
K
1
M
3
F
0
P
0
S
1
T
0
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 3 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 3 H: 4 I: 3 L: 2 K: 2 M: 1 F: 3 P: 0 S: 0 T: 1 W: 0 Y: 0 V: 2
Chemical Descriptors
25
C139H220N44O27S1
2971.61
12.71
+5
2.72
0.224
Evidence Records 18 records
Evidence 1 Activity

Activity

MIC
Antibacterial
6.31 µM

Target

V. alginolyticus

Source & Reference

NA

Other

active against Gram- bacteria V. alginolyticus (MIC 6.31 uM), V. anguillarum (MIC 6.31 uM), V. brasiliensis (MIC 3.16 uM), V. cholerae (MIC 3.16 uM),
Evidence 2 Activity

Activity

MIC
Antibacterial
6.31 µM

Target

V. anguillarum

Source & Reference

NA

Other

active against Gram- bacteria V. alginolyticus (MIC 6.31 uM), V. anguillarum (MIC 6.31 uM), V. brasiliensis (MIC 3.16 uM), V. cholerae (MIC 3.16 uM), V. fluvialis (MIC 6.31 uM), V.
Evidence 3 Activity

Activity

MIC
Antibacterial
3.16 µM

Target

V. brasiliensis

Source & Reference

NA

Other

tive against Gram- bacteria V. alginolyticus (MIC 6.31 uM), V. anguillarum (MIC 6.31 uM), V. brasiliensis (MIC 3.16 uM), V. cholerae (MIC 3.16 uM), V. fluvialis (MIC 6.31 uM), V. harveyi (MIC 3.16 uM), V. para
Evidence 4 Activity

Activity

MIC
Antibacterial
3.16 µM

Target

V. cholerae

Source & Reference

NA

Other

alginolyticus (MIC 6.31 uM), V. anguillarum (MIC 6.31 uM), V. brasiliensis (MIC 3.16 uM), V. cholerae (MIC 3.16 uM), V. fluvialis (MIC 6.31 uM), V. harveyi (MIC 3.16 uM), V. parahaemolyticus (MIC 3.16 uM),
Evidence 5 Activity

Activity

MIC
Antibacterial
6.31 µM

Target

V. fluvialis

Source & Reference

NA

Other

, V. anguillarum (MIC 6.31 uM), V. brasiliensis (MIC 3.16 uM), V. cholerae (MIC 3.16 uM), V. fluvialis (MIC 6.31 uM), V. harveyi (MIC 3.16 uM), V. parahaemolyticus (MIC 3.16 uM), V. plendidus (MIC 3.16 uM),
Evidence 6 Activity

Activity

MIC
Antibacterial
3.16 µM

Target

V. harveyi

Source & Reference

NA

Other

M), V. brasiliensis (MIC 3.16 uM), V. cholerae (MIC 3.16 uM), V. fluvialis (MIC 6.31 uM), V. harveyi (MIC 3.16 uM), V. parahaemolyticus (MIC 3.16 uM), V. plendidus (MIC 3.16 uM), V. vulnificus (MIC 3.16 u
Evidence 7 Activity

Activity

MIC
Antibacterial
3.16 µM

Target

V. parahaemolyticus

Source & Reference

NA

Other

.16 uM), V. cholerae (MIC 3.16 uM), V. fluvialis (MIC 6.31 uM), V. harveyi (MIC 3.16 uM), V. parahaemolyticus (MIC 3.16 uM), V. plendidus (MIC 3.16 uM), V. vulnificus (MIC 3.16 uM), A. hydrophila (MIC 3.16 uM), A.
Evidence 8 Activity

Activity

MIC
Antibacterial
3.16 µM

Target

V. plendidus

Source & Reference

NA

Other

V. fluvialis (MIC 6.31 uM), V. harveyi (MIC 3.16 uM), V. parahaemolyticus (MIC 3.16 uM), V. plendidus (MIC 3.16 uM), V. vulnificus (MIC 3.16 uM), A. hydrophila (MIC 3.16 uM), A. sobria (MIC 3.16 uM), A. ve
Evidence 9 Activity

Activity

MIC
Antibacterial
3.16 µM

Target

V. vulnificus

Source & Reference

NA

Other

V. harveyi (MIC 3.16 uM), V. parahaemolyticus (MIC 3.16 uM), V. plendidus (MIC 3.16 uM), V. vulnificus (MIC 3.16 uM), A. hydrophila (MIC 3.16 uM), A. sobria (MIC 3.16 uM), A. veronii (MIC 6.31 uM), Gram+ S.
Evidence 10 Activity

Activity

MIC
Antibacterial
3.16 µM

Target

A. hydrophila

Source & Reference

NA

Other

parahaemolyticus (MIC 3.16 uM), V. plendidus (MIC 3.16 uM), V. vulnificus (MIC 3.16 uM), A. hydrophila (MIC 3.16 uM), A. sobria (MIC 3.16 uM), A. veronii (MIC 6.31 uM), Gram+ S. aureus ATCC25923 or CMCC2600
Evidence 11 Activity

Activity

MIC
Antibacterial
3.16 µM

Target

A. sobria

Source & Reference

NA

Other

M), V. plendidus (MIC 3.16 uM), V. vulnificus (MIC 3.16 uM), A. hydrophila (MIC 3.16 uM), A. sobria (MIC 3.16 uM), A. veronii (MIC 6.31 uM), Gram+ S. aureus ATCC25923 or CMCC26003 (MIC 3.16 uM), and N. a
Evidence 12 Activity

Activity

MIC
Antibacterial
6.31 µM

Target

A. veronii

Source & Reference

NA

Other

6 uM), V. vulnificus (MIC 3.16 uM), A. hydrophila (MIC 3.16 uM), A. sobria (MIC 3.16 uM), A. veronii (MIC 6.31 uM), Gram+ S. aureus ATCC25923 or CMCC26003 (MIC 3.16 uM), and N. asteroides (MIC 3.16 uM). A
Evidence 13 Activity

Activity

MIC
Antibacterial
3.16 µM

Target

Staphylococcus aureus ATCC25923 or CMCC26003

Source & Reference

NA

Other

M), A. hydrophila (MIC 3.16 uM), A. sobria (MIC 3.16 uM), A. veronii (MIC 6.31 uM), Gram+ S. aureus ATCC25923 or CMCC26003 (MIC 3.16 uM), and N. asteroides (MIC 3.16 uM). Antibiofilm: inhibited biofilm formation: V. vulnificus
Evidence 14 Activity

Activity

MIC
Antibacterial
3.16 µM

Target

N. asteroides

Source & Reference

NA

Other

uM), A. veronii (MIC 6.31 uM), Gram+ S. aureus ATCC25923 or CMCC26003 (MIC 3.16 uM), and N. asteroides (MIC 3.16 uM). Antibiofilm: inhibited biofilm formation: V. vulnificus:48h:0.5MIC:10%CV inhibited biof
Evidence 15 Activity

Activity

100% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
100% Hemolysis | 200 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Defensing role of novel piscidins from largemouth bass (Micropterus salmoides) with evidence of bactericidal activities and inducible expressional delineation. | Microbiol Res | 2022
Evidence 16 Activity

Activity

54.33% Hemolysis
Toxicity
200 µg/mL
Hemolytic Cytotoxic
54.33% Hemolysis | 200 | µg/mL | target cell: Fish erythrocytes

Target

Fish erythrocytes

Source & Reference

NA
DBAASP
Defensing role of novel piscidins from largemouth bass (Micropterus salmoides) with evidence of bactericidal activities and inducible expressional delineation. | Microbiol Res | 2022
Evidence 17 Activity

Activity

67.28% Killing
Toxicity
200 µg/mL
Cytotoxic
67.28% Killing | 200 | µg/mL | target cell: Fathead minnow muscle cells (FHM)

Target

Fathead minnow muscle cells (FHM)

Source & Reference

NA
DBAASP
Defensing role of novel piscidins from largemouth bass (Micropterus salmoides) with evidence of bactericidal activities and inducible expressional delineation. | Microbiol Res | 2022
Evidence 18 Activity

Activity

66.36% Killing
Toxicity
200 µg/mL
Cytotoxic
66.36% Killing | 200 | µg/mL | target cell: Epithelioma papulosum cyprini cells (EPC)

Target

Epithelioma papulosum cyprini cells (EPC)

Source & Reference

NA
DBAASP
Defensing role of novel piscidins from largemouth bass (Micropterus salmoides) with evidence of bactericidal activities and inducible expressional delineation. | Microbiol Res | 2022