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Peptide record

TPDB19052

Antibacterial Toxicity standard
7 amino acids
Basic Information
3D PDB MODEL
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TPDB19052
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 7-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
FFWRRVK
Physicochemical Analysis
C52H75N15O8
ANDCEQGHILMPSTY
RF
1038.26
12.41
3
0
4
+3
-1.43
-0.571
41.43
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
5500
529.73
0
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
1
K
0
M
2
F
0
P
0
S
0
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 1 M: 0 F: 2 P: 0 S: 0 T: 0 W: 1 Y: 0 V: 1
Chemical Descriptors
7
C52H75N15O8
1038.26
12.41
+3
-1.43
-0.571
Evidence Records 2 records
Evidence 1 Activity

Activity

<5% Hemolysis
Toxicity
512 µM
Hemolytic Cytotoxic
<5% Hemolysis | 512 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Novel antibiotics effective against gram-positive and -negative multi-resistant bacteria with limited resistance. | PLoS Biol | 2019
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
NA | target cell: Human embryonic kidney HEK293 cells

Target

Human embryonic kidney HEK293 cells

Source & Reference

NA
DBAASP
Novel antibiotics effective against gram-positive and -negative multi-resistant bacteria with limited resistance. | PLoS Biol | 2019