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Peptide record

TPDB19029

HX-12B Antibacterial Anticancer standard
13 amino acids
Basic Information
3D PDB MODEL
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TPDB19029
HX-12B
Antibacterial Anticancer
Anti-infective peptides Cancer-related peptides
Peptipedia CancerPPD 2.0
standard
No
A 13-aa standard natural multi-activity (Antibacterial and Anticancer) peptide sequence curated from Peptipedia and CancerPPD 2.0, with an available 3D structural model.
Sequence
FFRKVLKLIRKIF
Physicochemical Analysis
C86H142N22O14
ANDCEQGHMPSTWY
KF
1708.21
12.43
5
0
8
+5
-0.47
0.654
142.31
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
2
L
3
K
0
M
3
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 2 K: 3 M: 0 F: 3 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
13
C86H142N22O14
1708.21
12.43
+5
-0.47
0.654
Free
L
Linear
Free
Antimicrobial
Synthetic derivative of Temporin-Pta
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
IC50 = 7.61 µM
Anticancer
7.61 µM

Target

Cervical Cancer
KB-C2
Cervix

Assay & Model

MTT assay
72-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2020

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.