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Peptide record

TPDB19028

HX-12A Antibacterial Anticancer standard
12 amino acids
Basic Information
3D PDB MODEL
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TPDB19028
HX-12A
Antibacterial Anticancer
Anti-infective peptides Cancer-related peptides
Peptipedia CancerPPD 2.0
standard
No
A 12-aa standard natural multi-activity (Antibacterial and Anticancer) peptide sequence curated from Peptipedia and CancerPPD 2.0, with an available 3D structural model.
Sequence
FFRKVLKLIRKI
Physicochemical Analysis
C77H133N21O13
ANDCEQGHMPSTWY
K
1561.04
12.43
5
0
7
+5
0.66
0.475
154.17
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
2
I
2
L
3
K
0
M
2
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 2 L: 2 K: 3 M: 0 F: 2 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
12
C77H133N21O13
1561.04
12.43
+5
0.66
0.475
Free
L
Linear
Free
Antimicrobial
Synthetic derivative of Temporin-Pta
Evidence Records 1 records
Evidence 1 Activity

Activity

IC50
IC50 = 6.45 µM
Anticancer
6.45 µM

Target

Cervical Cancer
KB-C2
Cervix

Assay & Model

MTT assay
72-h

Source & Reference

CancerPPD 2.0
CancerPPD2
2020

Other

Source Activity Label Source Definition
Anticancer
CancerPPD 2.0 manually curated experimentally verified anticancer peptide/protein annotation.