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Peptide record

TPDB19026

Antibacterial Antifungal Antiparasitic Hemolysis Toxicity standard
54 amino acids
Basic Information
3D PDB MODEL
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TPDB19026
Antibacterial Antifungal Antiparasitic Hemolysis Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb dbAMP dbAMP 3.0 PD_Hemolysis
standard
No
A 54-aa standard natural multi-activity (Antibacterial, Antifungal, Antiparasitic, and other sources) peptide sequence curated from Peptipedia, CAFPdb, dbAMP, and other sources, with an available 3D structural model.
Sequence
FFRHIKSFWKGAKAIFRGARQGWREHRALSKQRKMDQGGGGNEVDNGTPPYWQK
Physicochemical Analysis
C284H429N91O73S1
C
G
6318.16
11.47
14
4
17
+8
10.73
-1.244
34.44
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
17990
284.73
10
Residue Composition
number
4
A
6
R
2
N
2
D
0
C
2
E
4
Q
8
G
2
H
2
I
1
L
6
K
1
M
4
F
2
P
2
S
1
T
3
W
1
Y
1
V
Amino Acid Distribution
A: 4 R: 6 N: 2 D: 2 C: 0 E: 2 Q: 4 G: 8 H: 2 I: 2 L: 1 K: 6 M: 1 F: 4 P: 2 S: 2 T: 1 W: 3 Y: 1 V: 1
Chemical Descriptors
54
C284H429N91O73S1
6318.16
11.47
+8
10.73
-1.244
Evidence Records 6 records
Evidence 1 Activity

Activity

9.29±1.06% Hemolysis
Toxicity
1.25 µM
Hemolytic Cytotoxic
9.29±1.06% Hemolysis | 1.25 | µM | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Three new piscidins from orange-spotted grouper (Epinephelus coioides): Phylogeny, expression and functional characterization. | Fish Shellfish Immunol | 2017
Evidence 2 Activity

Activity

16.45±0.77% Hemolysis
Toxicity
2.5 µM
Hemolytic Cytotoxic
16.45±0.77% Hemolysis | 2.5 | µM | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Three new piscidins from orange-spotted grouper (Epinephelus coioides): Phylogeny, expression and functional characterization. | Fish Shellfish Immunol | 2017
Evidence 3 Activity

Activity

21.61±1.80% Hemolysis
Toxicity
5 µM
Hemolytic Cytotoxic
21.61±1.80% Hemolysis | 5 | µM | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Three new piscidins from orange-spotted grouper (Epinephelus coioides): Phylogeny, expression and functional characterization. | Fish Shellfish Immunol | 2017
Evidence 4 Activity

Activity

38.15±3.25% Hemolysis
Toxicity
10 µM
Hemolytic Cytotoxic
38.15±3.25% Hemolysis | 10 | µM | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Three new piscidins from orange-spotted grouper (Epinephelus coioides): Phylogeny, expression and functional characterization. | Fish Shellfish Immunol | 2017
Evidence 5 Activity

Activity

42.71±0.45% Hemolysis
Toxicity
20 µM
Hemolytic Cytotoxic
42.71±0.45% Hemolysis | 20 | µM | target cell: Rabbit erythrocytes

Target

Rabbit erythrocytes

Source & Reference

NA
DBAASP
Three new piscidins from orange-spotted grouper (Epinephelus coioides): Phylogeny, expression and functional characterization. | Fish Shellfish Immunol | 2017
Evidence 6 Hemolysis

Source & Reference

PD_Hemolysis
PD_Hemolysis