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Peptide record

TPDB19000

Antibacterial Toxicity modified_plain modified
22 amino acids
Basic Information
3D PDB MODEL
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TPDB19000
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 22-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
FFHHIFRXIVHVGKTIHRLVTG
Physicochemical Analysis
C120H184N36O24
ANDCEQMPSWY
H
2515.01
12.41
7
0
10
+3
2.08
0.473
110.45
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
2
Residue Composition
number
0
A
2
R
0
N
0
D
0
C
0
E
0
Q
2
G
4
H
3
I
1
L
1
K
0
M
3
F
0
P
0
S
2
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 0 R: 2 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 2 H: 4 I: 3 L: 1 K: 1 M: 0 F: 3 P: 0 S: 0 T: 2 W: 0 Y: 0 V: 3
Chemical Descriptors
22
C120H184N36O24
2515.01
12.41
+3
2.08
0.473
Evidence Records 1 records
Evidence 1 Activity

Activity

0% Hemolysis
Toxicity
200 µM
Hemolytic Cytotoxic
0% Hemolysis | 200 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Structural flexibility and the positive charges are the key factors in bacterial cell selectivity and membrane penetration of peptoid-substituted analog of Piscidin 1. | Biochim Biophys Acta | 2010