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Peptide record

TPDB18985

Antibacterial Antifungal Toxicity modified_plain modified
8 amino acids
Basic Information
3D PDB MODEL
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TPDB18985
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb dbAMP
modified_plain
Yes
A 8-aa modified multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia, CAFPdb, and dbAMP, with an available 3D structural model.
Modified, details unspecified
Sequence
FFFLXRIF
Physicochemical Analysis
C54H72N10O8
ANDCEQGHKMPSTWYV
F
989.23
11.05
1
0
6
+1
-4.58
1.875
97.50
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
0
A
1
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
1
I
1
L
0
K
0
M
4
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 0 R: 1 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 1 L: 1 K: 0 M: 0 F: 4 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
8
C54H72N10O8
989.23
11.05
+1
-4.58
1.875
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Hemolysis
Toxicity
95 µM
Hemolytic Cytotoxic
50% Hemolysis | 95 | µM | target cell: Rat erythrocytes

Target

Rat erythrocytes

Source & Reference

NA
DBAASP
Structure-Activity Relationship-based Optimization of Small Temporin-SHf Analogs with Potent Antibacterial Activity | ACS Chem Biol | 2015