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Peptide record

TPDB18964

Antibacterial Antifungal Toxicity modified_plain modified
11 amino acids
Basic Information
3D PDB MODEL
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TPDB18964
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb
modified_plain
Yes
A 11-aa modified multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia and CAFPdb, with an available 3D structural model.
Modified, details unspecified
Sequence
FDIXGLIKKVA
Physicochemical Analysis
C53H90N12O13
RNCEQHMPSTWY
IK
1103.37
9.88
2
1
6
+1
0.81
0.900
141.82
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
1
A
0
R
0
N
1
D
0
C
0
E
0
Q
1
G
0
H
2
I
1
L
2
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 1 H: 0 I: 2 L: 1 K: 2 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
11
C53H90N12O13
1103.37
9.88
+1
0.81
0.900
Evidence Records 2 records
Evidence 1 Activity

Activity

35% Hemolysis
Toxicity
50 µg/mL
Hemolytic Cytotoxic
35% Hemolysis | 50 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial Activity and Toxicity of Analogs of Wasp Venom EMP Peptides. Potential Influence of Oxidized Methionine | Antibiotics (Basel) | 2021
Evidence 2 Activity

Activity

50% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
50% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial Activity and Toxicity of Analogs of Wasp Venom EMP Peptides. Potential Influence of Oxidized Methionine | Antibiotics (Basel) | 2021