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Peptide record

TPDB18963

Antibacterial Antifungal Toxicity modified_plain modified
14 amino acids
Basic Information
3D PDB MODEL
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TPDB18963
Antibacterial Antifungal Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia CAFPdb
modified_plain
Yes
A 14-aa modified multi-activity (Antibacterial, Antifungal, and Toxicity) peptide sequence curated from Peptipedia and CAFPdb, with an available 3D structural model.
Modified, details unspecified
Sequence
FDIXGLIEEVAGAL
Physicochemical Analysis
C62H99N13O20
RNCQHKMPSTWY
AEGIL
1346.54
2.94
0
3
8
-3
2.15
1.136
146.43
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
2
A
0
R
0
N
1
D
0
C
2
E
0
Q
2
G
0
H
2
I
2
L
0
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
1
V
Amino Acid Distribution
A: 2 R: 0 N: 0 D: 1 C: 0 E: 2 Q: 0 G: 2 H: 0 I: 2 L: 2 K: 0 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 1
Chemical Descriptors
14
C62H99N13O20
1346.54
2.94
-3
2.15
1.136
Evidence Records 2 records
Evidence 1 Activity

Activity

35% Hemolysis
Toxicity
50 µg/mL
Hemolytic Cytotoxic
35% Hemolysis | 50 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial Activity and Toxicity of Analogs of Wasp Venom EMP Peptides. Potential Influence of Oxidized Methionine | Antibiotics (Basel) | 2021
Evidence 2 Activity

Activity

42% Hemolysis
Toxicity
100 µg/mL
Hemolytic Cytotoxic
42% Hemolysis | 100 | µg/mL | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Antimicrobial Activity and Toxicity of Analogs of Wasp Venom EMP Peptides. Potential Influence of Oxidized Methionine | Antibiotics (Basel) | 2021