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Peptide record

TPDB18955

RP444 Antibacterial Toxicity modified_plain modified
23 amino acids
Basic Information
3D PDB MODEL
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TPDB18955
RP444
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia DBAASP
modified_plain
Yes
A 23-aa modified multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia and DBAASP, with an available 3D structural model.
Modified, details unspecified
Sequence
FAXXFAXXFXXFAXXFAXFAFAF
Physicochemical Analysis
C90H104N14O15
RNDCEQGHILKMPSTWYV
F
1621.90
6.02
0
0
14
-0
-10.06
1.443
26.09
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
6
A
0
R
0
N
0
D
0
C
0
E
0
Q
0
G
0
H
0
I
0
L
0
K
0
M
8
F
0
P
0
S
0
T
0
W
0
Y
0
V
Amino Acid Distribution
A: 6 R: 0 N: 0 D: 0 C: 0 E: 0 Q: 0 G: 0 H: 0 I: 0 L: 0 K: 0 M: 0 F: 8 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 0
Chemical Descriptors
23
C90H104N14O15
1621.90
6.02
-0
-10.06
1.443
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Cell death
Toxicity
20 µg/mL
Cytotoxic
50% Cell death | 20 | µg/mL | target cell: Human keratinocytes HaCat

Target

Human keratinocytes HaCat

Source & Reference

NA
DBAASP
Designed Antimicrobial Peptides for Topical Treatment of Antibiotic Resistant Acne Vulgaris. | Antibiotics (Basel) | 2020
Evidence 2 Activity

Target

Cutibacterium acnes

Source & Reference

DBAASP