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Peptide record

TPDB18954

Antibacterial Anticancer Antiviral Toxicity standard
26 amino acids
Basic Information
3D PDB MODEL
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TPDB18954
Antibacterial Anticancer Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia ACP740 _ACP240 AntiCP 2.0 CancerPPD 2.0 SATPdb iACP-DRLF pep-lab AI4AVP dbAMP 3.0 DRAVP 2.0
standard
No
A 26-aa standard natural multi-activity (Antibacterial, Anticancer, Antiviral, and other sources) peptide sequence curated from Peptipedia, ACP740 _ACP240, AntiCP 2.0, and other sources, with an available 3D structural model.
Sequence
FAVGLRAIKRALKKLRRGVRKVAKDL
Physicochemical Analysis
C134H244N46O29
NCEQHMPSTWY
RK
2963.70
12.59
10
1
13
+9
6.10
-0.154
123.85
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
0
0.00
0
Residue Composition
number
4
A
5
R
0
N
1
D
0
C
0
E
0
Q
2
G
0
H
1
I
4
L
5
K
0
M
1
F
0
P
0
S
0
T
0
W
0
Y
3
V
Amino Acid Distribution
A: 4 R: 5 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 2 H: 0 I: 1 L: 4 K: 5 M: 0 F: 1 P: 0 S: 0 T: 0 W: 0 Y: 0 V: 3
Chemical Descriptors
26
C134H244N46O29
2963.70
12.59
+9
6.10
-0.154
Evidence Records 2 records
Evidence 1 Activity

Activity

50% Cytotoxicity
Toxicity
8.73 µM
Cytotoxic
50% Cytotoxicity | 8.73 | µM | target cell: Feline kidney epithelial CRFK cells

Target

Feline kidney epithelial CRFK cells

Source & Reference

NA
DBAASP
Inhibitory activity of synthetic peptide antibiotics on feline immunodeficiency virus infectivity in vitro. | J Virol | 2002
Evidence 2 Activity

Activity

Toxicity
Cytotoxic
Cytotoxicity: [Ref.12208971]CrFK cell:TC50=8.73 µM.

Source & Reference

NA
DRAMP
J Virol. 2002 Oct 76(19):9952-61.