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Peptide record

TPDB18944

Antibacterial Antifungal standard
73 amino acids
Basic Information
3D PDB MODEL
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TPDB18944
Antibacterial Antifungal
Anti-infective peptides
Peptipedia AFP-GFuse Antifungipept CAFPdb dbAMP
standard
No
A 73-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from Peptipedia, AFP-GFuse, Antifungipept, and other sources, with an available 3D structural model.
Sequence
FCHLCEDLIKDGKEAGDVALDVWLDEEIGSRCKDFGVLASECFKELKVAEHDIWEAIDQEIPEDKTCKEAKLC
Physicochemical Analysis
C362H565N91O118S6
NMY
E
8272.37
4.17
11
20
27
-11
30.67
-0.312
88.22
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
11375
137.51
10
Residue Composition
number
6
A
1
R
0
N
9
D
6
C
11
E
1
Q
4
G
2
H
5
I
7
L
8
K
0
M
3
F
1
P
2
S
1
T
2
W
0
Y
4
V
Amino Acid Distribution
A: 6 R: 1 N: 0 D: 9 C: 6 E: 11 Q: 1 G: 4 H: 2 I: 5 L: 7 K: 8 M: 0 F: 3 P: 1 S: 2 T: 1 W: 2 Y: 0 V: 4
Chemical Descriptors
73
C362H565N91O118S6
8272.37
4.17
-11
30.67
-0.312
Evidence Records 2 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

dbAMP

Other

Source Activity Label Source Definition
Antibacterial
dbAMP classified as Antibacterial under the Anti-bacterial function class.
Active against Gram-positive bacteria, yeast cells and amoebae by permeabilizing their membranes. SPP-12 binds to phospholipid membranes and forms pores in a pH-dependent manner characteristic of caenopores.
Evidence 2 Activity

Activity

Antifungal

Source & Reference

dbAMP CAFPdb Antifungipept

Other

Source Activity Label Source Definition
Antifungal
dbAMP classified under the Anti-fungal function class.
Active against Gram-positive bacteria, yeast cells and amoebae by permeabilizing their membranes. SPP-12 binds to phospholipid membranes and forms pores in a pH-dependent manner characteristic of caenopores.