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Peptide record

TPDB18933

Antibacterial Antifungal standard
22 amino acids
Basic Information
3D PDB MODEL
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TPDB18933
Antibacterial Antifungal
Anti-infective peptides
Peptipedia Antifungipept
standard
No
A 22-aa standard natural multi-activity (Antibacterial and Antifungal) peptide sequence curated from Peptipedia and Antifungipept, with an available 3D structural model.
Sequence
FAHWPDLGPGSPSVKKHGKVIM
Physicochemical Analysis
C111H170N30O27S1
RNCEQTY
GKP
2388.82
10.32
5
1
8
+2
3.65
-0.314
66.36
Mammalian: 1.1 hour Yeast: 3 min E.coli: 2 min
5500
230.24
2
Residue Composition
number
1
A
0
R
0
N
1
D
0
C
0
E
0
Q
3
G
2
H
1
I
1
L
3
K
1
M
1
F
3
P
2
S
0
T
1
W
0
Y
2
V
Amino Acid Distribution
A: 1 R: 0 N: 0 D: 1 C: 0 E: 0 Q: 0 G: 3 H: 2 I: 1 L: 1 K: 3 M: 1 F: 1 P: 3 S: 2 T: 0 W: 1 Y: 0 V: 2
Chemical Descriptors
22
C111H170N30O27S1
2388.82
10.32
+2
3.65
-0.314
Evidence Records 2 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

NA

Other

Active against E. tarda. At 83.72 uM, it killed S. aureus, M. lysodeikticus, E. tarda and V. harveyi (MBC 83.72 uM) at 41.86 uM, it killed A. caviae, A. hydrophila, 70% A. jandaei, A. veronil, V. alginolyticus, and V. parahaemolyticus (MBC 41.86 uM). Replaced 12/2017 updated 7/2021 .
Evidence 2 Activity

Activity

Antifungal

Source & Reference

Antifungipept

Other

Active against E. tarda. At 83.72 uM, it killed S. aureus, M. lysodeikticus, E. tarda and V. harveyi (MBC 83.72 uM) at 41.86 uM, it killed A. caviae, A. hydrophila, 70% A. jandaei, A. veronil, V. alginolyticus, and V. parahaemolyticus (MBC 41.86 uM). Replaced 12/2017 updated 7/2021 .