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Peptide record

TPDB18808

Antibacterial Toxicity standard
114 amino acids
Basic Information
3D PDB MODEL
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TPDB18808
Antibacterial Toxicity
Anti-infective peptides Toxicity and safety peptides
Peptipedia
standard
No
A 114-aa standard natural multi-activity (Antibacterial and Toxicity) peptide sequence curated from Peptipedia, with an available 3D structural model.
Sequence
EKRRGGRLCYCRRRFCVCVGREKRRGLRRLGRKIAHGVKKYGPTVLRIIRIAGEKRGFGCPLNQGACHRHCRSIRRRGGYCAGFFKQTCTCYRNEKRVDKPDYRPRPWPRPNSR
Physicochemical Analysis
C578H953N213O142S10
M
R
13478.87
11.73
38
6
29
+29
31.63
-1.072
50.44
Mammalian: 1 hour Yeast: 30 min E.coli: >10 hour
13575
100.71
25
Residue Composition
number
4
A
26
R
3
N
2
D
10
C
4
E
2
Q
14
G
3
H
5
I
5
L
9
K
0
M
4
F
7
P
2
S
3
T
1
W
5
Y
5
V
Amino Acid Distribution
A: 4 R: 26 N: 3 D: 2 C: 10 E: 4 Q: 2 G: 14 H: 3 I: 5 L: 5 K: 9 M: 0 F: 4 P: 7 S: 2 T: 3 W: 1 Y: 5 V: 5
Chemical Descriptors
114
C578H953N213O142S10
13478.87
11.73
+29
31.63
-1.072
Evidence Records 1 records
Evidence 1 Activity

Activity

1% Hemolysis
Toxicity
<6.3 µM
Hemolytic Cytotoxic
1% Hemolysis | <6.3 | µM | target cell: Human erythrocytes

Target

Human erythrocytes

Source & Reference

NA
DBAASP
Characterisation and evaluation of synthetic antimicrobial peptides against Bacillus globigii, Bacillus anthracis and Burkholderia thailandensis. | Int J Antimicrob Agents | 2010