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Peptide record

TPDB18688

Antibacterial Anticancer Antiviral Toxicity modified_plain modified
27 amino acids
Basic Information
3D PDB MODEL
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TPDB18688
Antibacterial Anticancer Antiviral Toxicity
Anti-infective peptides Cancer-related peptides Toxicity and safety peptides
Peptipedia
modified_plain
Yes
A 27-aa modified multi-activity (Antibacterial, Anticancer, Antiviral, and other sources) peptide sequence curated from Peptipedia, with an available 3D structural model.
Modified, details unspecified
Sequence
DWTKNIKDKIDKIIHDFVDKTLPDQGX
Physicochemical Analysis
C139H220N36O43
ARCEMSY
D
3083.49
5.36
6
6
8
-1
10.32
-0.970
82.96
Mammalian: 1.1 hour Yeast: 3 min E.coli: >10 hour
5500
178.37
4
Residue Composition
number
0
A
0
R
1
N
6
D
0
C
0
E
1
Q
1
G
1
H
4
I
1
L
5
K
0
M
1
F
1
P
0
S
2
T
1
W
0
Y
1
V
Amino Acid Distribution
A: 0 R: 0 N: 1 D: 6 C: 0 E: 0 Q: 1 G: 1 H: 1 I: 4 L: 1 K: 5 M: 0 F: 1 P: 1 S: 0 T: 2 W: 1 Y: 0 V: 1
Chemical Descriptors
27
C139H220N36O43
3083.49
5.36
-1
10.32
-0.970
Evidence Records 1 records
Evidence 1 Activity

Activity

50% Cytotoxicity
Toxicity
>=25 µM
Cytotoxic
50% Cytotoxicity | >=25 | µM | target cell: Human embryonic kidney HEK293T cells

Target

Human embryonic kidney HEK293T cells

Source & Reference

NA
DBAASP
Cholesterol-conjugated stapled peptides inhibit Ebola and Marburg viruses in vitro and in vivo. | Antiviral Res | 2019