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Peptide record

TPDB18687

Antibacterial Antifungal standard
20 amino acids
Basic Information
3D PDB MODEL
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TPDB18687
Antibacterial Antifungal
Anti-infective peptides
Peptipedia Antifungipept CAFPdb
standard
No
A 20-aa standard-residue multi-activity (Antibacterial and Antifungal) peptide sequence curated from Peptipedia, Antifungipept, and CAFPdb, with an available 3D structural model.
Sequence
DWTCSKWSCLVCDDCSVELT
Physicochemical Analysis

Sequence-only estimates for a linear peptide with free termini, not experimentally measured molecular properties. Mass and formula exclude cyclization and disulfide formation. The optical estimates assume paired cysteines, 280 nm, 1 g/L and a 1 cm path. The N-end rule estimate is not a measured plasma half-life.

C96H145N23O34S4
ARNQGHIMFPY
C
2293.58
3.50
1
4
6
-3
1.31
0.125
68.00
Mammalian: 1.1 hour Yeast: 3 min E.coli: >10 hour
11250
4.90
9
Residue Composition
number
0
A
0
R
0
N
3
D
4
C
1
E
0
Q
0
G
0
H
0
I
2
L
1
K
0
M
0
F
0
P
3
S
2
T
2
W
0
Y
2
V
Amino Acid Distribution
A: 0 R: 0 N: 0 D: 3 C: 4 E: 1 Q: 0 G: 0 H: 0 I: 0 L: 2 K: 1 M: 0 F: 0 P: 0 S: 3 T: 2 W: 2 Y: 0 V: 2
Chemical Descriptors
20 reviewed residue count
C96H145N23O34S4 sequence-only estimate (linear, free termini)
2293.58 sequence-only estimate (linear, free termini)
3.50 sequence-only estimate (linear, free termini)
-3 sequence-only estimate (linear, free termini)
1.31 sequence-only estimate (linear, free termini)
0.125 sequence-only estimate (linear, free termini)
Evidence Records 2 records
Evidence 1 Activity

Activity

Antibacterial

Source & Reference

NA

Other

Active against Gram+ M. luteus LB 14110, S. aureus ATCC 6538, L. ivanovii BUG 496, E. faecalis JH 2-2, Gram- bacteria E. coli ATCC 8739, S. typhimurium, A. tumefaciens C58, P. savastanoi pv. savastanoi, P. aeruginosa ATCC 49189, fungistatic against C. tropicalis R2 CIP203 and Fusarium. sp. based on inhibition zone 13-33 mm).
Evidence 2 Activity

Activity

Antifungal

Source & Reference

CAFPdb Antifungipept

Other

Active against Gram+ M. luteus LB 14110, S. aureus ATCC 6538, L. ivanovii BUG 496, E. faecalis JH 2-2, Gram- bacteria E. coli ATCC 8739, S. typhimurium, A. tumefaciens C58, P. savastanoi pv. savastanoi, P. aeruginosa ATCC 49189, fungistatic against C. tropicalis R2 CIP203 and Fusarium. sp. based on inhibition zone 13-33 mm).